Table 2

Incidence of myeloproliferative markers and hereditary thrombocythemia markers in 32 children with ET

MarkerSporadic thrombocythemiaFamilial thrombocythemia
No. 20 12 
JAK2V617F mutation, no. patients (%) 8 (40) 
Exon 12 JAK2 mutations, no. patients (%) 
TPO mutations, no. patients (%) 
MPL mutations, no. patients (%) 10 (83) 
EEC growth, no. patients (%) 10 (50) 3 (25) 
Clonal hematopoiesis, no. patients* 8/13 0/5 
ET diagnosis, no. patients (%) 20 (100) 12 (100) 
MarkerSporadic thrombocythemiaFamilial thrombocythemia
No. 20 12 
JAK2V617F mutation, no. patients (%) 8 (40) 
Exon 12 JAK2 mutations, no. patients (%) 
TPO mutations, no. patients (%) 
MPL mutations, no. patients (%) 10 (83) 
EEC growth, no. patients (%) 10 (50) 3 (25) 
Clonal hematopoiesis, no. patients* 8/13 0/5 
ET diagnosis, no. patients (%) 20 (100) 12 (100) 

The number of patients fulfilling the proposed revised WHO diagnostic criteria for ET is shown in the lower part of the table.

*

Number of patients with clonal hematopoiesis among all female patients.

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