Molecular subtype classification of pediatric DLBCL
| Pathologic diagnosis* . | Molecular diagnosis† . | |||
|---|---|---|---|---|
| GCB . | ABC . | PMBL . | NC . | |
| DLBCL | 5 | 1 | 2 | 3 |
| BL | 8 | 1 | 0 | 1 |
| Total | 13 | 2 | 2 | 4 |
| Pathologic diagnosis* . | Molecular diagnosis† . | |||
|---|---|---|---|---|
| GCB . | ABC . | PMBL . | NC . | |
| DLBCL | 5 | 1 | 2 | 3 |
| BL | 8 | 1 | 0 | 1 |
| Total | 13 | 2 | 2 | 4 |
NC indicates nonclassifiable cases with a diagnostic probability of < 90% by Bayesian classification.
Pathologic diagnosis is the specimen diagnosis based on pathology review provided by the Cooperative Human Tissue Network.
Molecular diagnosis is the Bayesian classification of cases using 2 DLBCL subtype gene signatures: 1 that distinguishes GCB and ABC DLBCL subtypes,23 and a PMBL gene signature.27