Table 3

Most commonly reported AEs (>10% of the population)

AE, n (%)All gradesGrade 3 or 4 eventsGrade 5 events
Infection* 42 (36) 3 (3) 
Rash 18 (16) 
Urticaria 16 (14) 1 (1) 
Fatigue 16 (14) 
Pruritus 15 (13) 
Nausea 14 (12) 
Cough 14 (12) 2 (2) 
Neutropenia 14 (12) 13 (11) 1 (1) 
Pyrexia 13 (11) 
Sepsis   2 (2) 
AE, n (%)All gradesGrade 3 or 4 eventsGrade 5 events
Infection* 42 (36) 3 (3) 
Rash 18 (16) 
Urticaria 16 (14) 1 (1) 
Fatigue 16 (14) 
Pruritus 15 (13) 
Nausea 14 (12) 
Cough 14 (12) 2 (2) 
Neutropenia 14 (12) 13 (11) 1 (1) 
Pyrexia 13 (11) 
Sepsis   2 (2) 
*

The most frequent types of infections were upper respiratory tract infections.

Includes 1 case of grade 3 febrile neutropenia.

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