Table 2.

New thromboembolic events (n = 7) in patients with ITP who developed a platelet count <50 × 109/L while receiving AC and their TH2 scores

PatientInitial TH2 scoreAC decision after initial encounterRepeat TH2 score*AC decision after repeat encounterThrombotic event
Negative Withheld Positive Withheld Fatal ischemic stroke 
Withheld Positive Withheld Fatal PE 
Withheld Positive Resumed Ischemic stroke 
Negative Withheld Positive Withheld Iliac artery thrombus 
Negative Continued NA Arterial and venous limb thrombus 
Negative Withheld Positive Resumed Arterial limb thrombus 
Withheld Positive Resumed Ischemic stroke 
PatientInitial TH2 scoreAC decision after initial encounterRepeat TH2 score*AC decision after repeat encounterThrombotic event
Negative Withheld Positive Withheld Fatal ischemic stroke 
Withheld Positive Withheld Fatal PE 
Withheld Positive Resumed Ischemic stroke 
Negative Withheld Positive Withheld Iliac artery thrombus 
Negative Continued NA Arterial and venous limb thrombus 
Negative Withheld Positive Resumed Arterial limb thrombus 
Withheld Positive Resumed Ischemic stroke 

PE, pulmonary embolism.

*

Repeat TH2 score once platelet count improved >50 × 109/L.

Subtherapeutic international normalized ratio after resumption of warfarin.

Cancer-associated thrombosis on warfarin (metastatic squamous cell cancer).

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