Table 1.

TH2 score with 2 thrombotic risk factors and 2 bleeding risk factors for patients with thrombocytopenia and an indication for antithrombotic therapy

Risk assessmentScore
Thrombotic risk factors  
 High thrombotic risk* +1 
 Recent ITP treatment +1 
Bleeding risk factors  
 Platelets <20 × 109/L −1 
 Major bleed (excluding skin) at presentation −1 
Overall score Nil or positive (excess thrombotic risk); negative (excess bleeding risk) 
Risk assessmentScore
Thrombotic risk factors  
 High thrombotic risk* +1 
 Recent ITP treatment +1 
Bleeding risk factors  
 Platelets <20 × 109/L −1 
 Major bleed (excluding skin) at presentation −1 
Overall score Nil or positive (excess thrombotic risk); negative (excess bleeding risk) 
*

Atrial fibrillation congestive heart failure, hypertension, age ≥75 years, diabetes, prior stroke, vascular disease, age 65 to 74 years, and sex category >5; unprovoked, recurrent, or cancer-associated thrombosis; antiphospholipid antibody syndrome.

Intravenous immune globulin within 2 weeks or thrombopoietin receptor agonist or splenectomy within 4 weeks.

Grade 2 by the ITP Bleeding Score.12 

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