Predictors of progression to total blood loss of more than 2500 mL
| . | Total blood loss (mL) . | Crude OR (95% CI) . | Adjusted OR* (95% CI) . | P . | |
|---|---|---|---|---|---|
| . | ≤2500 (n = 310) . | >2500 (n = 37) . | |||
| Age (y) | n = 310 | n = 37 | 1.05 (0.99-1.11) | — | — |
| Mean (SD) | 29.81 (5.83) | 31.32 (5.55) | |||
| BMI (kg/m2) | n = 304 | n = 37 | 0.997 (0.94-1.06) | — | — |
| Mean (SD) | 27.19 (5.82) | 27.08 (5.25) | |||
| Hb on admission (g/L) | n = 309 | n = 37 | 1.03 (0.77-1.36) | — | — |
| Mean (SD) | 12.03 (1.20) | 12.07 (1.28) | |||
| Hb study entry (g/L) | n = 302 | n = 36 | 0.69 (0.56-0.86) | 0.87 | .388 |
| Mean (SD) | 10.38 (1.58) | 9.41 (1.97) | (0.64-1.19) | ||
| Clauss fibrinogen (g/L) | n = 297 | n = 35 | 0.43 (0.30-0.63) | 0.93 (0.49-1.74) | .813 |
| Mean (SD) | 3.91 (1.12) | 2.94 (1.32) | |||
| Fibtem A5 (mm) | n = 285 | n = 33 | 0.82 (0.77-0.89) | 0.85 (0.77-0.95) | .002 |
| Mean (SD) | 20.09 (6.03) | 13.73 (6.61) | |||
| Mode of delivery, n (%) | |||||
| Elective cesarean | 58 (93.5) | 4 (6.5) | 1.00 | — | — |
| Nonelective cesarean | 111 (89.5) | 13 (10.5) | 1.70 (0.53-5.44) | — | — |
| Instrumental vaginal | 65 (87.8) | 9 (12.2) | 2.01 (0.59-6.87) | — | — |
| Uncomplicated vaginal | 76 (87.4) | 11 (12.6) | 2.10 (0.64-6.93) | — | — |
| PT, n (%) | |||||
| ≤13 s (normal) | 296 (90.8) | 30 (9.2) | 1.00 | 1.00 | — |
| >13 s (abnormal) | 1 (16.7) | 5 (83.3) | 49.33 (5.58-436.26) | 91.87 (0.58-14479.17) | .080 |
| aPPT, n (%) | |||||
| ≤38 s (normal) | 296 (90.2) | 32 (9.8) | 1.00 | 1.00 | — |
| >38 s (abnormal) | 1 (25.0) | 3 (75.0) | 27.75 (2.80-274.3) | 0.11 (0.001-42.66) | .471 |
| Primary cause of PPH, n (%) | |||||
| Surgical bleed | 120 (95.2) | 6 (4.8) | 1.00 | 1.00 | — |
| Uterine atony | 125 (85.6) | 21 (14.4) | 3.56 (1.31-8.61) | 2.74 (0.97-7.77) | .058 |
| Placenta retained | 32 (88.9) | 4 (11.1) | 2.50 (0.67-9.40) | 1.42 (0.26-7.76) | .685 |
| Abruption | 11 (78.6) | 3 (21.4) | 5.46 (1.20-24.87) | 0.49 (0.04-5.81) | .571 |
| Other/no cause | 22 (88.0) | 3 (12.0) | 2.73 (0.63-11.73) | 2.03 (0.39-10.48) | .398 |
| . | Total blood loss (mL) . | Crude OR (95% CI) . | Adjusted OR* (95% CI) . | P . | |
|---|---|---|---|---|---|
| . | ≤2500 (n = 310) . | >2500 (n = 37) . | |||
| Age (y) | n = 310 | n = 37 | 1.05 (0.99-1.11) | — | — |
| Mean (SD) | 29.81 (5.83) | 31.32 (5.55) | |||
| BMI (kg/m2) | n = 304 | n = 37 | 0.997 (0.94-1.06) | — | — |
| Mean (SD) | 27.19 (5.82) | 27.08 (5.25) | |||
| Hb on admission (g/L) | n = 309 | n = 37 | 1.03 (0.77-1.36) | — | — |
| Mean (SD) | 12.03 (1.20) | 12.07 (1.28) | |||
| Hb study entry (g/L) | n = 302 | n = 36 | 0.69 (0.56-0.86) | 0.87 | .388 |
| Mean (SD) | 10.38 (1.58) | 9.41 (1.97) | (0.64-1.19) | ||
| Clauss fibrinogen (g/L) | n = 297 | n = 35 | 0.43 (0.30-0.63) | 0.93 (0.49-1.74) | .813 |
| Mean (SD) | 3.91 (1.12) | 2.94 (1.32) | |||
| Fibtem A5 (mm) | n = 285 | n = 33 | 0.82 (0.77-0.89) | 0.85 (0.77-0.95) | .002 |
| Mean (SD) | 20.09 (6.03) | 13.73 (6.61) | |||
| Mode of delivery, n (%) | |||||
| Elective cesarean | 58 (93.5) | 4 (6.5) | 1.00 | — | — |
| Nonelective cesarean | 111 (89.5) | 13 (10.5) | 1.70 (0.53-5.44) | — | — |
| Instrumental vaginal | 65 (87.8) | 9 (12.2) | 2.01 (0.59-6.87) | — | — |
| Uncomplicated vaginal | 76 (87.4) | 11 (12.6) | 2.10 (0.64-6.93) | — | — |
| PT, n (%) | |||||
| ≤13 s (normal) | 296 (90.8) | 30 (9.2) | 1.00 | 1.00 | — |
| >13 s (abnormal) | 1 (16.7) | 5 (83.3) | 49.33 (5.58-436.26) | 91.87 (0.58-14479.17) | .080 |
| aPPT, n (%) | |||||
| ≤38 s (normal) | 296 (90.2) | 32 (9.8) | 1.00 | 1.00 | — |
| >38 s (abnormal) | 1 (25.0) | 3 (75.0) | 27.75 (2.80-274.3) | 0.11 (0.001-42.66) | .471 |
| Primary cause of PPH, n (%) | |||||
| Surgical bleed | 120 (95.2) | 6 (4.8) | 1.00 | 1.00 | — |
| Uterine atony | 125 (85.6) | 21 (14.4) | 3.56 (1.31-8.61) | 2.74 (0.97-7.77) | .058 |
| Placenta retained | 32 (88.9) | 4 (11.1) | 2.50 (0.67-9.40) | 1.42 (0.26-7.76) | .685 |
| Abruption | 11 (78.6) | 3 (21.4) | 5.46 (1.20-24.87) | 0.49 (0.04-5.81) | .571 |
| Other/no cause | 22 (88.0) | 3 (12.0) | 2.73 (0.63-11.73) | 2.03 (0.39-10.48) | .398 |
Based on the complete case set (n = 298).