Table 1.

Genetic changes found in earliest inferable progenitor of FL

Genetic changeApproximate frequency in FL, %
Translocation of BCL2 80-90 
Mutations in 1 or more chromatin-modifier genes 95 
Acquisition of N-glycosylation sites in IGV region of BCR 75-90 
Genetic changeApproximate frequency in FL, %
Translocation of BCL2 80-90 
Mutations in 1 or more chromatin-modifier genes 95 
Acquisition of N-glycosylation sites in IGV region of BCR 75-90 
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