Characteristics of the DISCOVeRY-BMT cohort
| Patient characteristics . | N (%) . | P* . | |
|---|---|---|---|
| Cohort 1 (n = 1970) . | Cohort 2 (n = 503) . | ||
| Age, y | <.01 | ||
| Mean | 43.0 | 46.7 | |
| Range | 0.45-74.5 | 0-78 | |
| Donor age, y | <.01 | ||
| Mean | 34.2 | 31.6 | |
| Range | 18.4-61.2 | 18.2-60 | |
| Sex | NS | ||
| Female | 858 (44) | 218 (43) | |
| Male | 1112 (56) | 285 (57) | |
| Donor sex | <.01 | ||
| Female | 564 (32) | 118 (25) | |
| Male | 1177 (68) | 362 (75) | |
| Disease | <.01 | ||
| ALL | 442 (22) | 41 (8) | |
| AML | 1196 (61) | 327 (65) | |
| MDS | 332 (17) | 135 (27) | |
| ALL disease status | NS | ||
| Early | 362 (82) | 33 (80) | |
| Advanced | 80 (18) | 8 (20) | |
| AML disease status | .01 | ||
| Early | 843 (70) | 254 (78) | |
| Advanced | 353 (30) | 73 (22) | |
| MDS disease status | <.01 | ||
| Early | 221 (67) | 46 (34) | |
| Advanced | 111 (33) | 89 (66) | |
| Graft source | <.01 | ||
| Bone marrow | 694 (35) | 114 (23) | |
| Peripheral blood | 1276 (65) | 389 (77) | |
| Patient characteristics . | N (%) . | P* . | |
|---|---|---|---|
| Cohort 1 (n = 1970) . | Cohort 2 (n = 503) . | ||
| Age, y | <.01 | ||
| Mean | 43.0 | 46.7 | |
| Range | 0.45-74.5 | 0-78 | |
| Donor age, y | <.01 | ||
| Mean | 34.2 | 31.6 | |
| Range | 18.4-61.2 | 18.2-60 | |
| Sex | NS | ||
| Female | 858 (44) | 218 (43) | |
| Male | 1112 (56) | 285 (57) | |
| Donor sex | <.01 | ||
| Female | 564 (32) | 118 (25) | |
| Male | 1177 (68) | 362 (75) | |
| Disease | <.01 | ||
| ALL | 442 (22) | 41 (8) | |
| AML | 1196 (61) | 327 (65) | |
| MDS | 332 (17) | 135 (27) | |
| ALL disease status | NS | ||
| Early | 362 (82) | 33 (80) | |
| Advanced | 80 (18) | 8 (20) | |
| AML disease status | .01 | ||
| Early | 843 (70) | 254 (78) | |
| Advanced | 353 (30) | 73 (22) | |
| MDS disease status | <.01 | ||
| Early | 221 (67) | 46 (34) | |
| Advanced | 111 (33) | 89 (66) | |
| Graft source | <.01 | ||
| Bone marrow | 694 (35) | 114 (23) | |
| Peripheral blood | 1276 (65) | 389 (77) | |
ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; MDS, myelodysplastic syndrome; NS, not significant.
Kolmogorov-Smirnov test was used to compare the age distribution between cohorts. Fisher’s exact test and χ2 test weres used to compare binary and multicategorical data between the 2 cohorts.