Research needs in PTS
| Research needs . |
|---|
| PTS prevention |
| Studies to improve understanding of the pathophysiology of PTS and to suggest future therapeutic targets for PTS prevention |
| Validation of clinical prediction rules to predict risk of PTS |
| Studies of the relative effect of DOACs compared with VKAs on the risk of PTS |
| Studies exploring the role of statins and targeted anti-inflammatory medications as an adjunct to anticoagulation for PTS prevention |
| Studies of the effectiveness of ECS to prevent PTS in high-risk subgroups |
| RCTs of CDT, PCDT, and surgical thrombectomy in high-risk patients with long-term follow-up and analysis of cost effectiveness and benefit-to-harm ratio for PTS prevention |
| Management of established PTS |
| RCTs evaluating the long-term benefit of venoactive drugs for PTS management |
| RCTs to assess the long-term effectiveness and safety of endovascular and surgical techniques to treat established PTS |
| Research needs . |
|---|
| PTS prevention |
| Studies to improve understanding of the pathophysiology of PTS and to suggest future therapeutic targets for PTS prevention |
| Validation of clinical prediction rules to predict risk of PTS |
| Studies of the relative effect of DOACs compared with VKAs on the risk of PTS |
| Studies exploring the role of statins and targeted anti-inflammatory medications as an adjunct to anticoagulation for PTS prevention |
| Studies of the effectiveness of ECS to prevent PTS in high-risk subgroups |
| RCTs of CDT, PCDT, and surgical thrombectomy in high-risk patients with long-term follow-up and analysis of cost effectiveness and benefit-to-harm ratio for PTS prevention |
| Management of established PTS |
| RCTs evaluating the long-term benefit of venoactive drugs for PTS management |
| RCTs to assess the long-term effectiveness and safety of endovascular and surgical techniques to treat established PTS |