Last available chimerism data before 1 year, death, graft failure, DLI, and/or second transplant
ID . | Primary diagnosis . | Sustained engraftment or failure event . | Day of 1-year follow-up or failure event . | Last available chimerism . | Minimum recorded chimersim . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Day of unfractionated sample . | Unfractionated sample, % donor . | Unfractionated sample type . | Day of T-cell sample . | T-cell sample, % donor . | T-cell sample type . | % Donor . | Day of sample . | Sample type . | ||||
1 | CAEBV | Sustained engraftment | 365 | — | — | — | 102 | 100 | Blood | 69 | 12 | T-cell |
2 | HLH | Sustained engraftment | 365 | — | — | — | 124 | 100 | Blood | 85 | 26 | T-cell |
3 | HLH | Death | 39 | 19 | 99 | Blood | 37 | 53 | Blood | 53 | 37 | T-cell |
4 | HLH | Sustained engraftment | 364 | 144 | 100 | Blood | 144 | 100 | Blood | 95 | 25 | T-cell |
5 | HLH | DLI | 53 | 39 | 54 | Blood | — | — | — | 4 | 18 | T-cell |
6 | HIGM1 | DLI | 115 | — | — | — | 98 | 97 | Blood | 92 | 76 | Marrow |
7 | HLH | DLI | 60 | 52 | 55 | Blood | — | — | — | 55 | 52 | Marrow |
8 | HLH | DLI | 73 | 70 | 24 | Blood | 70 | 37 | Blood | 2 | 170 | Marrow |
9 | HLH | Sustained engraftment | 365 | — | — | — | 354 | 95 | Blood | 89 | 35 | T-cell |
10 | HLH | DLI | 90 | 83 | 81 | Blood | 76 | 63 | Blood | 21 | 356 | Marrow |
11 | HLH | DLI | 74 | 73 | 28 | Blood | 73 | 82 | Blood | 5 | 307 | Marrow |
12 | HLH | SGF | 70 | 54 | 38 | Blood | 54 | 14 | Blood | 4 | 70 | T-cell |
13 | HLH | DLI | 100 | 84 | 34 | Blood | 84 | 89 | Blood | 32 | 68 | Marrow |
14 | HLH | Sustained engraftment | 365 | — | — | — | 245 | 95 | Blood | 93 | 175 | T-cell |
15 | HLH | DLI | 126 | 101 | 64 | Blood | 101 | 57 | Blood | 7 | 318 | Marrow |
16 | HLH | DLI | 123 | 88 | 30 | Blood | 88 | 14 | Blood | 12 | 53 | T-cell |
17 | HLH | Death | 253 | 248 | 100 | Blood | — | — | 100 | 24 | Marrow | |
18 | CAEBV | Sustained engraftment | 365 | — | — | — | 361 | 80 | Blood | 31 | 46 | T-cell |
19 | HLH | Death | 45 | 39 | 96 | Blood | 39 | 96 | Blood | 96 | 27 | Marrow |
20 | HLH | Sustained engraftment | 361 | — | — | — | 188 | 99 | Blood | 56 | 39 | T-cell |
21 | HLH | PGF | 42 | 41 | 0 | Blood | 41 | 0 | Blood | 0 | 27 | Marrow |
22 | IPEX | DLI | 138 | 105 | 15 | Blood | — | — | — | 8 | 163 | Marrow |
23 | HLH | Sustained engraftment | 365 | 175 | 98 | Blood | — | — | — | 97 | 371 | Marrow |
24 | HLH | Sustained engraftment | 363 | 333 | 90 | Blood | 333 | 97 | Blood | 90 | 27 | T-cell |
25 | HLH | Sustained engraftment | 365 | 275 | 100 | Blood | — | — | — | 100 | 16 | Marrow |
26 | CGD | SGF | 98 | — | — | — | 85 | 18 | Blood | 0 | 106 | T-cell |
27 | CGD | DLI | 124 | 89 | 5 | Blood | 89 | 10 | Blood | 4 | 152 | Marrow |
28 | HLH | Death | 96 | 84 | 100 | Blood | — | — | — | 100 | 28 | Marrow |
29 | HLH | Sustained engraftment | 365 | — | — | — | 362 | 100 | Blood | 100 | 21 | T-cell |
30 | HLH | Sustained engraftment | 365 | 312 | 100 | Blood | — | — | — | 96 | 84 | Marrow |
31 | HLH | Death | 246 | 243 | 99 | Blood | — | — | — | 67 | 26 | Marrow |
32 | CGD | Sustained engraftment | 351 | 169 | 96 | Blood | 169 | 96 | Blood | 96 | 56 | Marrow |
33 | HLH | Sustained engraftment | 356 | 342 | 23 | Blood | 342 | 79 | Blood | 23 | 342 | Marrow |
34 | CGD | Sustained engraftment | 365 | 70 | 93 | Blood | — | — | — | 93 | 70 | Marrow |
35 | HLH | Sustained engraftment | 365 | 286 | 100 | Blood | — | — | — | 99 | 113 | Marrow |
36 | HIGM1 | DLI | 99 | 78 | 91 | Blood | — | — | — | 0 | 122 | T-cell |
37 | HLH | Death | 75 | 71 | 18 | Marrow | 70 | 19 | Blood | 18 | 71 | Marrow |
38 | HLH | Second TXP | 363 | 351 | 71 | Blood | 351 | 91 | Blood | 71 | 351 | Marrow |
39 | HLH | Second TXP | 124 | 100 | 78 | Blood | — | — | — | 78 | 100 | Marrow |
40 | HLH | Sustained engraftment | 365 | 238 | 100 | Blood | — | — | — | 99 | 41 | Marrow |
41 | HLH | Sustained engraftment | 365 | — | — | — | 216 | 100 | Blood | 95 | 81 | T-cell |
42 | CGD | PGF | 42 | 19 | 0 | Blood | 29 | 0 | Blood | 0 | 19 | Marrow |
43 | HLH | DLI | 62 | — | — | — | 50 | 46 | Blood | 17 | 68 | T-cell |
44 | HLH | DLI | 145 | 97 | 82 | Blood | 88 | 68 | Blood | 44 | 287 | Marrow |
45 | IPEX | Death | 52 | 28 | 100 | Blood | 28 | 100 | Blood | 100 | 28 | Marrow |
46 | CAEBV | Death | 61 | 32 | 100 | Marrow | — | — | — | 100 | 32 | Marrow |
ID . | Primary diagnosis . | Sustained engraftment or failure event . | Day of 1-year follow-up or failure event . | Last available chimerism . | Minimum recorded chimersim . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Day of unfractionated sample . | Unfractionated sample, % donor . | Unfractionated sample type . | Day of T-cell sample . | T-cell sample, % donor . | T-cell sample type . | % Donor . | Day of sample . | Sample type . | ||||
1 | CAEBV | Sustained engraftment | 365 | — | — | — | 102 | 100 | Blood | 69 | 12 | T-cell |
2 | HLH | Sustained engraftment | 365 | — | — | — | 124 | 100 | Blood | 85 | 26 | T-cell |
3 | HLH | Death | 39 | 19 | 99 | Blood | 37 | 53 | Blood | 53 | 37 | T-cell |
4 | HLH | Sustained engraftment | 364 | 144 | 100 | Blood | 144 | 100 | Blood | 95 | 25 | T-cell |
5 | HLH | DLI | 53 | 39 | 54 | Blood | — | — | — | 4 | 18 | T-cell |
6 | HIGM1 | DLI | 115 | — | — | — | 98 | 97 | Blood | 92 | 76 | Marrow |
7 | HLH | DLI | 60 | 52 | 55 | Blood | — | — | — | 55 | 52 | Marrow |
8 | HLH | DLI | 73 | 70 | 24 | Blood | 70 | 37 | Blood | 2 | 170 | Marrow |
9 | HLH | Sustained engraftment | 365 | — | — | — | 354 | 95 | Blood | 89 | 35 | T-cell |
10 | HLH | DLI | 90 | 83 | 81 | Blood | 76 | 63 | Blood | 21 | 356 | Marrow |
11 | HLH | DLI | 74 | 73 | 28 | Blood | 73 | 82 | Blood | 5 | 307 | Marrow |
12 | HLH | SGF | 70 | 54 | 38 | Blood | 54 | 14 | Blood | 4 | 70 | T-cell |
13 | HLH | DLI | 100 | 84 | 34 | Blood | 84 | 89 | Blood | 32 | 68 | Marrow |
14 | HLH | Sustained engraftment | 365 | — | — | — | 245 | 95 | Blood | 93 | 175 | T-cell |
15 | HLH | DLI | 126 | 101 | 64 | Blood | 101 | 57 | Blood | 7 | 318 | Marrow |
16 | HLH | DLI | 123 | 88 | 30 | Blood | 88 | 14 | Blood | 12 | 53 | T-cell |
17 | HLH | Death | 253 | 248 | 100 | Blood | — | — | 100 | 24 | Marrow | |
18 | CAEBV | Sustained engraftment | 365 | — | — | — | 361 | 80 | Blood | 31 | 46 | T-cell |
19 | HLH | Death | 45 | 39 | 96 | Blood | 39 | 96 | Blood | 96 | 27 | Marrow |
20 | HLH | Sustained engraftment | 361 | — | — | — | 188 | 99 | Blood | 56 | 39 | T-cell |
21 | HLH | PGF | 42 | 41 | 0 | Blood | 41 | 0 | Blood | 0 | 27 | Marrow |
22 | IPEX | DLI | 138 | 105 | 15 | Blood | — | — | — | 8 | 163 | Marrow |
23 | HLH | Sustained engraftment | 365 | 175 | 98 | Blood | — | — | — | 97 | 371 | Marrow |
24 | HLH | Sustained engraftment | 363 | 333 | 90 | Blood | 333 | 97 | Blood | 90 | 27 | T-cell |
25 | HLH | Sustained engraftment | 365 | 275 | 100 | Blood | — | — | — | 100 | 16 | Marrow |
26 | CGD | SGF | 98 | — | — | — | 85 | 18 | Blood | 0 | 106 | T-cell |
27 | CGD | DLI | 124 | 89 | 5 | Blood | 89 | 10 | Blood | 4 | 152 | Marrow |
28 | HLH | Death | 96 | 84 | 100 | Blood | — | — | — | 100 | 28 | Marrow |
29 | HLH | Sustained engraftment | 365 | — | — | — | 362 | 100 | Blood | 100 | 21 | T-cell |
30 | HLH | Sustained engraftment | 365 | 312 | 100 | Blood | — | — | — | 96 | 84 | Marrow |
31 | HLH | Death | 246 | 243 | 99 | Blood | — | — | — | 67 | 26 | Marrow |
32 | CGD | Sustained engraftment | 351 | 169 | 96 | Blood | 169 | 96 | Blood | 96 | 56 | Marrow |
33 | HLH | Sustained engraftment | 356 | 342 | 23 | Blood | 342 | 79 | Blood | 23 | 342 | Marrow |
34 | CGD | Sustained engraftment | 365 | 70 | 93 | Blood | — | — | — | 93 | 70 | Marrow |
35 | HLH | Sustained engraftment | 365 | 286 | 100 | Blood | — | — | — | 99 | 113 | Marrow |
36 | HIGM1 | DLI | 99 | 78 | 91 | Blood | — | — | — | 0 | 122 | T-cell |
37 | HLH | Death | 75 | 71 | 18 | Marrow | 70 | 19 | Blood | 18 | 71 | Marrow |
38 | HLH | Second TXP | 363 | 351 | 71 | Blood | 351 | 91 | Blood | 71 | 351 | Marrow |
39 | HLH | Second TXP | 124 | 100 | 78 | Blood | — | — | — | 78 | 100 | Marrow |
40 | HLH | Sustained engraftment | 365 | 238 | 100 | Blood | — | — | — | 99 | 41 | Marrow |
41 | HLH | Sustained engraftment | 365 | — | — | — | 216 | 100 | Blood | 95 | 81 | T-cell |
42 | CGD | PGF | 42 | 19 | 0 | Blood | 29 | 0 | Blood | 0 | 19 | Marrow |
43 | HLH | DLI | 62 | — | — | — | 50 | 46 | Blood | 17 | 68 | T-cell |
44 | HLH | DLI | 145 | 97 | 82 | Blood | 88 | 68 | Blood | 44 | 287 | Marrow |
45 | IPEX | Death | 52 | 28 | 100 | Blood | 28 | 100 | Blood | 100 | 28 | Marrow |
46 | CAEBV | Death | 61 | 32 | 100 | Marrow | — | — | — | 100 | 32 | Marrow |