Table 2.

Sensitivity, specificity, positive-predictive value, and negative-predictive value analyses for 1-year NRM

SensitivitySpecificityPPVNPV
Test cohort 0.70 0.74 0.55 0.85 
Validation cohort 1 0.80 0.76 0.58 0.91 
Validation cohort 2 0.63 0.93 0.58 0.91 
Minnesota risk Early treatment response     
 Standard  Response 0.50 0.86 0.29 0.94 
 Standard  Nonresponse 0.55 0.84 0.46 0.88 
 High*  Response NA NA NA NA 
 High  Nonresponse 0.94 0.54 0.84 0.78 
SensitivitySpecificityPPVNPV
Test cohort 0.70 0.74 0.55 0.85 
Validation cohort 1 0.80 0.76 0.58 0.91 
Validation cohort 2 0.63 0.93 0.58 0.91 
Minnesota risk Early treatment response     
 Standard  Response 0.50 0.86 0.29 0.94 
 Standard  Nonresponse 0.55 0.84 0.46 0.88 
 High*  Response NA NA NA NA 
 High  Nonresponse 0.94 0.54 0.84 0.78 

NPV, negative-predictive value; PPV, positive-predictive value.

*

Too few patients with Minnesota high risk and early treatment response to calculate sensitivity, specificity, positive-predictive value, and negative-predictive value

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