Characteristics of the 2 patients at the time of diagnosis
| . | Patient 1 . | Patient 2 . |
|---|---|---|
| Age, y | 69 | 83 |
| Sex, M/F | M | M |
| Hemoglobin level, g/L | 168 | 194 |
| Hematocrit, % | 51.3 | 53 |
| Platelet count, 109/L | 658 | 575 |
| White blood cells, 109/L | 7.6 | 7.5 |
| Erythropoietin level, mIU/mL | 5.9 | 2.8 |
| Bone marrow biopsy | PV | N/A |
| RCM | Increased | N/A |
| JAK2V617F mutation | Negative | Negative |
| JAK2 exon 12 mutation | Negative | Negative |
| JAK2 exon 13 mutation | Negative | N/A |
| JAK2 exon 14 mutation | Negative | N/A |
| MPL mutation | Negative | Negative |
| BCR-ABL1 mutation | Negative | Negative |
| CALR mutation | Positive | Positive |
| . | Patient 1 . | Patient 2 . |
|---|---|---|
| Age, y | 69 | 83 |
| Sex, M/F | M | M |
| Hemoglobin level, g/L | 168 | 194 |
| Hematocrit, % | 51.3 | 53 |
| Platelet count, 109/L | 658 | 575 |
| White blood cells, 109/L | 7.6 | 7.5 |
| Erythropoietin level, mIU/mL | 5.9 | 2.8 |
| Bone marrow biopsy | PV | N/A |
| RCM | Increased | N/A |
| JAK2V617F mutation | Negative | Negative |
| JAK2 exon 12 mutation | Negative | Negative |
| JAK2 exon 13 mutation | Negative | N/A |
| JAK2 exon 14 mutation | Negative | N/A |
| MPL mutation | Negative | Negative |
| BCR-ABL1 mutation | Negative | Negative |
| CALR mutation | Positive | Positive |
F, female; M, male; mIU/ml, milli International Unit per millimeter; N/A, not available.