Table 2.

Proportion of VTE and bleeding in pregnant women with essential thrombocythemia

No LMWHLMWH*
Antepartum period   
 VTE risk (%) 2.5 (95% CI, 1.3-4.3; I2 0%) (n = 407) 0.0 (95% CI, 0.0-5.7; I2 0%) (n = 82) 
 Bleeding risk (%) 4.0 (95% CI, 1.5-7.8; I2 53.8%) (n = 407) 0.0 (95% CI, 0.0-5.7; I2 0%) (n = 82) 
Postpartum period   
 VTE risk (%) 4.4 (95% CI, 1.2-9.5; I2 48%) (n = 229) 0.0 (95% CI, 0.0-4.6; I2 0%) (n = 96) 
 Bleeding risk (%) 2.9 (95% CI, 1.4-5.0; I2 0%) (n = 309) 2.9 (95% CI, 0.1-9.6; I2 0.1%) (n = 97) 
No LMWHLMWH*
Antepartum period   
 VTE risk (%) 2.5 (95% CI, 1.3-4.3; I2 0%) (n = 407) 0.0 (95% CI, 0.0-5.7; I2 0%) (n = 82) 
 Bleeding risk (%) 4.0 (95% CI, 1.5-7.8; I2 53.8%) (n = 407) 0.0 (95% CI, 0.0-5.7; I2 0%) (n = 82) 
Postpartum period   
 VTE risk (%) 4.4 (95% CI, 1.2-9.5; I2 48%) (n = 229) 0.0 (95% CI, 0.0-4.6; I2 0%) (n = 96) 
 Bleeding risk (%) 2.9 (95% CI, 1.4-5.0; I2 0%) (n = 309) 2.9 (95% CI, 0.1-9.6; I2 0.1%) (n = 97) 
*

LMWH use in the antepartum setting is defined as 4 weeks or more of LMWH use during pregnancy.

Including placental abruption.

Excluding first trimester losses.

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