Cellular and exosomal miRNA profiles of KMS-11-HR cells
| Ct value . | miRNA . | (1) Acute hypoxia−, KMS-11-HR↑ . | miRNA . | (2) Acute hypoxia↑, KMS-11-HR↑ . | ||
|---|---|---|---|---|---|---|
| Fold change (vs parental cell) . | Fold change (vs parental cell) . | |||||
| Exosome . | Cell . | Exosome . | Cell . | |||
| 25-30 | miR-425 | 1.7072 | 2.196 | miR-210 | 13.9761 | 16.5659 |
| miR-335 | 6.5755 | 7.0668 | ||||
| 30-35 | miR-132 | 1.9641 | 5.6163 | |||
| miR-518b | 1.6252 | 3.0374 | ||||
| miR-328 | 1.9408 | 4.8109 | ||||
| miR-200c | 2.3988 | 3.1656 | ||||
| miR-331-5p | 1.7919 | 2.0219 | ||||
| miR-135b | 5.9424 | 2.0893 | ||||
| Ct value . | miRNA . | (1) Acute hypoxia−, KMS-11-HR↑ . | miRNA . | (2) Acute hypoxia↑, KMS-11-HR↑ . | ||
|---|---|---|---|---|---|---|
| Fold change (vs parental cell) . | Fold change (vs parental cell) . | |||||
| Exosome . | Cell . | Exosome . | Cell . | |||
| 25-30 | miR-425 | 1.7072 | 2.196 | miR-210 | 13.9761 | 16.5659 |
| miR-335 | 6.5755 | 7.0668 | ||||
| 30-35 | miR-132 | 1.9641 | 5.6163 | |||
| miR-518b | 1.6252 | 3.0374 | ||||
| miR-328 | 1.9408 | 4.8109 | ||||
| miR-200c | 2.3988 | 3.1656 | ||||
| miR-331-5p | 1.7919 | 2.0219 | ||||
| miR-135b | 5.9424 | 2.0893 | ||||
After the cellular and exosomal miRNAs were extracted by a fold change of <1.5 and Ct value, they were subdivided into 2 groups: (1) miRNAs upregulated only in HR-MM cells (Acute hypoxia−, KMS-11-HR↑), and (2) miRNAs upregulated in both acute hypoxia and HR-MM cells (Acute hypoxia↑, KMS-11-HR↑).