Table 1.

Intestinal bacteria associations in allo-HCT

BacteriaEffect on GVHD/HCTComment
Clostridium cluster XIVa/Blautia Positive Reduced during chemotherapy treatment50,51  
Low relative abundance associated with increased GVHD mortality in HCT patients66  
Low abundance associated with IBD72  
Ameliorates experimental GVHD in mice65  
Lactobacillus Positive Improves survival and reduces experimental aGVHD in mice53,94  
Reported as a safe supplement to HCT patients95  
Enterococcus Negative Increased during chemotherapy treatment50-52  
Intestinal dominance associated with blood stream infection after HCT55,80  
BacteriaEffect on GVHD/HCTComment
Clostridium cluster XIVa/Blautia Positive Reduced during chemotherapy treatment50,51  
Low relative abundance associated with increased GVHD mortality in HCT patients66  
Low abundance associated with IBD72  
Ameliorates experimental GVHD in mice65  
Lactobacillus Positive Improves survival and reduces experimental aGVHD in mice53,94  
Reported as a safe supplement to HCT patients95  
Enterococcus Negative Increased during chemotherapy treatment50-52  
Intestinal dominance associated with blood stream infection after HCT55,80  
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