Top differentially expressed genes in human Tfh and Teff cells
| Gene . | Mean Tfh . | Mean Teff . | Absolute difference . | Log fold change . | FDR . |
|---|---|---|---|---|---|
| PDCD1 | 1596.6 | 276.8 | 1319.8 | 2.2 | 0.0035 |
| CXCR5 | 1395.1 | 410.6 | 984.6 | 1.6 | 0.0240 |
| TOX2 | 1018.7 | 297.1 | 721.6 | 1.6 | 0.0397 |
| TRIM8 | 504.6 | 162.8 | 341.8 | 1.6 | 0.0138 |
| GNG4 | 335.6 | 15.6 | 320.0 | 3.2 | 0.0009 |
| NBEAL2 | 118.8 | 424.2 | 305.4 | −1.6 | 0.0217 |
| FAM43A | 359.6 | 74.7 | 284.9 | 2.0 | 0.0066 |
| BCL6 | 392.7 | 125.5 | 267.3 | 1.5 | 0.0454 |
| KCNK5 | 325.5 | 68.7 | 256.8 | 2.1 | 0.0004 |
| MYO7A | 273.0 | 37.5 | 235.6 | 2.4 | 0.0061 |
| KIAA1324 | 327.3 | 123.4 | 203.9 | 1.3 | 0.0468 |
| CCR7 | 41.2 | 244.9 | 203.7 | −2.4 | 0.0007 |
| ATP2B4 | 93.6 | 289.9 | 196.4 | −1.6 | 0.0052 |
| VIM | 21.3 | 205.6 | 184.3 | −2.8 | 0.0004 |
| CORO1B | 274.0 | 91.4 | 182.6 | 1.5 | 0.0148 |
| AAK1 | 44.0 | 223.3 | 179.3 | −2.3 | 0.0000 |
| IL7R | 24.0 | 195.9 | 171.9 | −2.8 | 0.0001 |
| MIAT | 58.5 | 219.9 | 161.4 | −1.9 | 0.0331 |
| PREX1 | 78.7 | 232.4 | 153.7 | −1.5 | 0.0446 |
| GIMAP4 | 88.3 | 236.8 | 148.4 | −1.4 | 0.0494 |
| Gene . | Mean Tfh . | Mean Teff . | Absolute difference . | Log fold change . | FDR . |
|---|---|---|---|---|---|
| PDCD1 | 1596.6 | 276.8 | 1319.8 | 2.2 | 0.0035 |
| CXCR5 | 1395.1 | 410.6 | 984.6 | 1.6 | 0.0240 |
| TOX2 | 1018.7 | 297.1 | 721.6 | 1.6 | 0.0397 |
| TRIM8 | 504.6 | 162.8 | 341.8 | 1.6 | 0.0138 |
| GNG4 | 335.6 | 15.6 | 320.0 | 3.2 | 0.0009 |
| NBEAL2 | 118.8 | 424.2 | 305.4 | −1.6 | 0.0217 |
| FAM43A | 359.6 | 74.7 | 284.9 | 2.0 | 0.0066 |
| BCL6 | 392.7 | 125.5 | 267.3 | 1.5 | 0.0454 |
| KCNK5 | 325.5 | 68.7 | 256.8 | 2.1 | 0.0004 |
| MYO7A | 273.0 | 37.5 | 235.6 | 2.4 | 0.0061 |
| KIAA1324 | 327.3 | 123.4 | 203.9 | 1.3 | 0.0468 |
| CCR7 | 41.2 | 244.9 | 203.7 | −2.4 | 0.0007 |
| ATP2B4 | 93.6 | 289.9 | 196.4 | −1.6 | 0.0052 |
| VIM | 21.3 | 205.6 | 184.3 | −2.8 | 0.0004 |
| CORO1B | 274.0 | 91.4 | 182.6 | 1.5 | 0.0148 |
| AAK1 | 44.0 | 223.3 | 179.3 | −2.3 | 0.0000 |
| IL7R | 24.0 | 195.9 | 171.9 | −2.8 | 0.0001 |
| MIAT | 58.5 | 219.9 | 161.4 | −1.9 | 0.0331 |
| PREX1 | 78.7 | 232.4 | 153.7 | −1.5 | 0.0446 |
| GIMAP4 | 88.3 | 236.8 | 148.4 | −1.4 | 0.0494 |