ARE-del>WT chimera mice exhibited thrombocytopenia, the first sign of BM failure (n = 8)
| . | WT>WT (mean ± SD) . | ARE-del>WT (mean ± SD) . | P . |
|---|---|---|---|
| WBC, K/μL | 9.08 ± 0.63 | 7.5 ± 0.69 | .13 |
| RBC, M/μL | 11.12 ± 0.16 | 10.4 ± 0.68 | .32 |
| Platelets, K/μL | 688 ± 36 | 389.6 ± 77 | .0043 |
| . | WT>WT (mean ± SD) . | ARE-del>WT (mean ± SD) . | P . |
|---|---|---|---|
| WBC, K/μL | 9.08 ± 0.63 | 7.5 ± 0.69 | .13 |
| RBC, M/μL | 11.12 ± 0.16 | 10.4 ± 0.68 | .32 |
| Platelets, K/μL | 688 ± 36 | 389.6 ± 77 | .0043 |
Blood was collected via heart puncture into tubes containing EDTA. CBC was performed within 3 hours after collection.