Table 1

Acceptance of the Champlin criteria as the characteristics defining a RIC regimen at the RIC Regimen Workshop convened by the CIBMTR

CriterionPercentage of HCT professionals that strongly agree or agree
Results in reversible myelosuppression (usually within 28 d) when given without stem cell support 67 
Results in mixed chimerism in a proportion of patients at the time of first assessment 71 
Associated with a low rate of nonhematologic toxicity 71 
CriterionPercentage of HCT professionals that strongly agree or agree
Results in reversible myelosuppression (usually within 28 d) when given without stem cell support 67 
Results in mixed chimerism in a proportion of patients at the time of first assessment 71 
Associated with a low rate of nonhematologic toxicity 71 

Adapted from Giralt et al.104 

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