Table 1

Landmark analysis for predictive value of MRD for PFS by N-PCR and RQ-PCR

TimeMedian follow-up (mo)Patients assessed (positive/negative)PFS at median follow up
N-PCRRQ-PCR
Positive (%)Negative (%)P valuePositive (%)Negative (%)P value
M5 38 29/71 62 69 .34 54 72 .11 
M8 34 15/84 39 72 .007 74 <.001 
M12 30 11/65 54 78 .042 78 <.001 
M18 24 5/72 40 81 .013 34 78 .079 
M24 19 9/60 44 90 <.001 20 88 <.001 
TimeMedian follow-up (mo)Patients assessed (positive/negative)PFS at median follow up
N-PCRRQ-PCR
Positive (%)Negative (%)P valuePositive (%)Negative (%)P value
M5 38 29/71 62 69 .34 54 72 .11 
M8 34 15/84 39 72 .007 74 <.001 
M12 30 11/65 54 78 .042 78 <.001 
M18 24 5/72 40 81 .013 34 78 .079 
M24 19 9/60 44 90 <.001 20 88 <.001 
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