Table 1

PB progenitors (total CFU-C/mL PB) before and after PHZ challenge

AnimalDay 0Day 4Day 6
Controls 85.7 ± 22.4 (n = 10) 572.3 ± 103.0 (n = 11) 344.8 ± 66.1 (n = 20) 
β1Δ 1742 ± 358 (n = 17) * 2985 ± 1382 (n = 8) 
    P < .02  < .05 
β1ΔTx 1405 ± 219 (n = 10) 14 997 ± 6117 (n = 5) 2877 ± 1047 (n = 5) 
    P < .05 < .05 < .02 
α4Δ 1226 ± 12 (n = 7) 11 308 ± 1455 (n = 3) 6812 ± 1252 (n = 6) 
    P < .05 < .01 < .01 
AnimalDay 0Day 4Day 6
Controls 85.7 ± 22.4 (n = 10) 572.3 ± 103.0 (n = 11) 344.8 ± 66.1 (n = 20) 
β1Δ 1742 ± 358 (n = 17) * 2985 ± 1382 (n = 8) 
    P < .02  < .05 
β1ΔTx 1405 ± 219 (n = 10) 14 997 ± 6117 (n = 5) 2877 ± 1047 (n = 5) 
    P < .05 < .05 < .02 
α4Δ 1226 ± 12 (n = 7) 11 308 ± 1455 (n = 3) 6812 ± 1252 (n = 6) 
    P < .05 < .01 < .01 

P values are versus controls.

*

Counts are available on 2 moribund mice (377 ± 131 CFU-C/mL PB) and another mouse (> 2000 CFU-C/mL PB).

Control mice transplanted with control cells had 2505 ± 807 CFU-C/mL PB; n = 7 at day 4 after PHZ.

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