Notch1 mutations and Fbxw7 LOH in F1 hybrid Tp53+/− mouse thymic lymphomas
| Tumor ID . | Notch1 mutation status* . | Fbxw7 locus . |
|---|---|---|
| F1-1 | 7342_7343insTG | LOH |
| F1-2 | Wild-type | LOH |
| F1-3 | Wild-type | LOH |
| F1-4 | Wild-type | LOH |
| F1-5 | 7114_7115insGGCAACACAGCCTCACCTGGTGCAGACCC | LOH |
| F1-6 | Wild-type | ROH |
| F1-7 | Wild-type | LOH |
| F1-8 | Wild-type | LOH |
| F1-9 | 7265_7275GCCCCAGCAGT > CAGC | LOH |
| F1-10 | Wild-type | LOH |
| F1-11 | Wild-type | LOH |
| F1-12 | 7260_7261insGG | LOH |
| F1-13 | 7140_7141insCA | LOH |
| F1-14 | 7083_7084insT | LOH |
| F1-15 | 7039_7042AATA > GCCCT | LOH |
| F1-16 | Wild-type | LOH |
| F1-17 | Wild-type | LOH |
| F1-18 | Wild-type | LOH |
| F1-19 | Wild-type | LOH |
| F1-20 | Wild-type | LOH |
| F1-21 | 7216_7217insG | LOH |
| F1-22 | 7216_7217insACCTGGGC; 7229_7260del | LOH |
| F1-23 | Wild-type | LOH |
| F1-24 | Wild-type | LOH |
| F1-25 | 7082G > CCC | ROH |
| F1-26 | Wild-type | ROH |
| F1-27† | 7271_7272insGCCG | LOH |
| F1-28 | 7252G > CCC | ROH |
| F1-29 | Wild-type | LOH |
| F1-30 | Wild-type | LOH |
| F1-31 | 7391_7392insA | ROH |
| F1-32 | Wild-type | LOH |
| F1-33 | 7244_7344del | LOH |
| F1-34 | 7237_7485del | LOH |
| F1-35 | 7292_7596del | LOH |
| Tumor ID . | Notch1 mutation status* . | Fbxw7 locus . |
|---|---|---|
| F1-1 | 7342_7343insTG | LOH |
| F1-2 | Wild-type | LOH |
| F1-3 | Wild-type | LOH |
| F1-4 | Wild-type | LOH |
| F1-5 | 7114_7115insGGCAACACAGCCTCACCTGGTGCAGACCC | LOH |
| F1-6 | Wild-type | ROH |
| F1-7 | Wild-type | LOH |
| F1-8 | Wild-type | LOH |
| F1-9 | 7265_7275GCCCCAGCAGT > CAGC | LOH |
| F1-10 | Wild-type | LOH |
| F1-11 | Wild-type | LOH |
| F1-12 | 7260_7261insGG | LOH |
| F1-13 | 7140_7141insCA | LOH |
| F1-14 | 7083_7084insT | LOH |
| F1-15 | 7039_7042AATA > GCCCT | LOH |
| F1-16 | Wild-type | LOH |
| F1-17 | Wild-type | LOH |
| F1-18 | Wild-type | LOH |
| F1-19 | Wild-type | LOH |
| F1-20 | Wild-type | LOH |
| F1-21 | 7216_7217insG | LOH |
| F1-22 | 7216_7217insACCTGGGC; 7229_7260del | LOH |
| F1-23 | Wild-type | LOH |
| F1-24 | Wild-type | LOH |
| F1-25 | 7082G > CCC | ROH |
| F1-26 | Wild-type | ROH |
| F1-27† | 7271_7272insGCCG | LOH |
| F1-28 | 7252G > CCC | ROH |
| F1-29 | Wild-type | LOH |
| F1-30 | Wild-type | LOH |
| F1-31 | 7391_7392insA | ROH |
| F1-32 | Wild-type | LOH |
| F1-33 | 7244_7344del | LOH |
| F1-34 | 7237_7485del | LOH |
| F1-35 | 7292_7596del | LOH |