Table 1 Type and frequency of Notch1... | American Society of Hematology

Table 1

Type and frequency of Notch1 mutations in murine thymic lymphoma

Genotype	n*	PEST domain mutations	Percent with Notch1 mutations
Tp53^+/−	24	10	42
Tp53^−/−	23	9	39
Tp53^+/− and Fbxw7^+/−	9	0	0†
Tp53^−/− and Fbxw7^+/⁻	9	0	0†
F1 hybrid (Tp53^+/−)	35	16	46

Genotype	n*	PEST domain mutations	Percent with Notch1 mutations
Tp53^+/−	24	10	42
Tp53^−/−	23	9	39
Tp53^+/− and Fbxw7^+/−	9	0	0†
Tp53^−/− and Fbxw7^+/⁻	9	0	0†
F1 hybrid (Tp53^+/−)	35	16	46

HD indicates heterodimerization; and PEST, proline-glutamic acid-serine-threonine.

Total number of thymic lymphomas examined.

P < .03.