Gene alterations shared in OPM2 cells after either CRBN knockdown or lenalidomide treatment
| Down-regulated . | Up-regulated . | |||
|---|---|---|---|---|
| AGPS | HAUS7///TREX2 | ROR1 | ADAT3 | HLA-DRB1///HLA-DRB4 |
| AJAP1 | HINT3 | RRP1B | ATXN1 | HLA-DRB1///HLA-DRB4 |
| APTX | HS3ST3B1 | SEC24A | AUTS2 | IFIH1 |
| BCL11B | ITPR1 | SEL1L | BTBD7 | IGF2BP3 |
| BEST3 | LOC730631 | SETD7 | C10orf10 | LIMA1 |
| BID | LOC84740 | SETMAR | C2orf68 | LRRC4C |
| C12orf66 | LPL | SLC7A2 | CARD16 | MAML2 |
| C13orf1 | LRRC8B | SMCR7L | CASP1 | 2-Mar |
| C18orf54 | MMACHC | SMEK2 | CTTNBP2 | MB |
| C7orf68 | MRS2 | SNHG3 | DCC | NFIB |
| CEP72 | MTAP | SNRPN | DHTKD1 | NMI |
| CNKSR2 | MYB | STAMBPL1 | DLEU2 | PCBP2 |
| COX11 | NEK6 | SUV39H2 | DNAJC5B | PLOD2 |
| DFFA | NETO2 | TET1 | ELF3 | PTEN |
| DNAJC25 | NUDCD1 | TMEM33 | EXTL2 | PTPRM |
| DTNA | NUP43 | TMEM64 | FCHO2 | RASGRP3 |
| EIF3M | ORC5L | TNFRSF21 | GIMAP2 | RCAN3 |
| FAM76B | PDK1 | TRIM4 | HIPK2 | RTP4 |
| FANCI | PGM2 | USP9X | HIST1H2AD///HIST1H3D | SUMF1 |
| FKBP11 | PPIF | WDR4 | HIST1H2BG | TMEM185A |
| FLJ25006 | PPP2R1B | WDR72 | HIST2H4A///HIST2H4B | UTRN |
| GABRB2 | RAD18 | ZNF148 | HLA-DPB1 | WDFY3 |
| GALNTL4 | RFC3 | ZNF561 | HLA-DQA1 | |
| GINS4 | RGS1 | ZNF706 | HLA-DQA1/// HLA-DRB1///HLA-DRB3 | |
| GNPNAT1 | RGS16 | ZWILCH | ||
| Down-regulated . | Up-regulated . | |||
|---|---|---|---|---|
| AGPS | HAUS7///TREX2 | ROR1 | ADAT3 | HLA-DRB1///HLA-DRB4 |
| AJAP1 | HINT3 | RRP1B | ATXN1 | HLA-DRB1///HLA-DRB4 |
| APTX | HS3ST3B1 | SEC24A | AUTS2 | IFIH1 |
| BCL11B | ITPR1 | SEL1L | BTBD7 | IGF2BP3 |
| BEST3 | LOC730631 | SETD7 | C10orf10 | LIMA1 |
| BID | LOC84740 | SETMAR | C2orf68 | LRRC4C |
| C12orf66 | LPL | SLC7A2 | CARD16 | MAML2 |
| C13orf1 | LRRC8B | SMCR7L | CASP1 | 2-Mar |
| C18orf54 | MMACHC | SMEK2 | CTTNBP2 | MB |
| C7orf68 | MRS2 | SNHG3 | DCC | NFIB |
| CEP72 | MTAP | SNRPN | DHTKD1 | NMI |
| CNKSR2 | MYB | STAMBPL1 | DLEU2 | PCBP2 |
| COX11 | NEK6 | SUV39H2 | DNAJC5B | PLOD2 |
| DFFA | NETO2 | TET1 | ELF3 | PTEN |
| DNAJC25 | NUDCD1 | TMEM33 | EXTL2 | PTPRM |
| DTNA | NUP43 | TMEM64 | FCHO2 | RASGRP3 |
| EIF3M | ORC5L | TNFRSF21 | GIMAP2 | RCAN3 |
| FAM76B | PDK1 | TRIM4 | HIPK2 | RTP4 |
| FANCI | PGM2 | USP9X | HIST1H2AD///HIST1H3D | SUMF1 |
| FKBP11 | PPIF | WDR4 | HIST1H2BG | TMEM185A |
| FLJ25006 | PPP2R1B | WDR72 | HIST2H4A///HIST2H4B | UTRN |
| GABRB2 | RAD18 | ZNF148 | HLA-DPB1 | WDFY3 |
| GALNTL4 | RFC3 | ZNF561 | HLA-DQA1 | |
| GINS4 | RGS1 | ZNF706 | HLA-DQA1/// HLA-DRB1///HLA-DRB3 | |
| GNPNAT1 | RGS16 | ZWILCH | ||