Complete response rates (CR/CRu) according to FcγRIIa 131 and FcγRIIIa 158 SNP carrier state
| . | CHOP-14 (n = 249) . | R-CHOP-14 (n = 263) . |
|---|---|---|
| FcγRIIa 131R/R (n = 64) | 23/33 (69.7%) | 25/31 (80.6%) |
| FcγRIIa 131R/H (n = 235) | 86/114 (75.4%) | 98/121 (81.0 %) |
| FcγRIIa 131H/H (n = 213) | 74/102 (72.5%) | 92/111 (82.9%) |
| Fisher exact test: P value | .75 | .90 |
| Armitage trend test | .95 | .70 |
| FcγRIIIa 158V/V (n = 145) | 51/69 (73.9%) | 66/76 (86.8%) |
| FcγRIIIa 158V/F (n = 271) | 101/131 (77.1%) | 114/140 (81.4%) |
| FcγRIIIa 158F/F (n = 96) | 31/49 (63.3%) | 35/47 (74.5%) |
| Fisher exact test: P value | .17 | .23 |
| Armitage trend test | .27 | .08 |
| . | CHOP-14 (n = 249) . | R-CHOP-14 (n = 263) . |
|---|---|---|
| FcγRIIa 131R/R (n = 64) | 23/33 (69.7%) | 25/31 (80.6%) |
| FcγRIIa 131R/H (n = 235) | 86/114 (75.4%) | 98/121 (81.0 %) |
| FcγRIIa 131H/H (n = 213) | 74/102 (72.5%) | 92/111 (82.9%) |
| Fisher exact test: P value | .75 | .90 |
| Armitage trend test | .95 | .70 |
| FcγRIIIa 158V/V (n = 145) | 51/69 (73.9%) | 66/76 (86.8%) |
| FcγRIIIa 158V/F (n = 271) | 101/131 (77.1%) | 114/140 (81.4%) |
| FcγRIIIa 158F/F (n = 96) | 31/49 (63.3%) | 35/47 (74.5%) |
| Fisher exact test: P value | .17 | .23 |
| Armitage trend test | .27 | .08 |