Demographic and clinical characteristics
| Characteristics . | Value . |
|---|---|
| No. | 104 |
| Age, y (mean ± SD) | 45 ± 15 |
| Female, no. (%) | 82 (79) |
| IgG isotype, no. (%) | 86 (83) |
| dRVVT mixing (mean ± SD) | 1.78 ± 0.5 |
| IgG aCL, GPL units (mean ± SD) | 102 ± 91 |
| IgG aβ2GPI, units (mean ± SD) | 123 ± 154 |
| IgM isotype, no. (%) | |
| dRVVT mixing | 18 (17) |
| IgM aCL, GPL units (mean ± SD) | 1.42 ± 0.3 |
| IgM aβ2GPI, units (mean ± SD) | 81 ± 58 |
| Reason for initial testing, no. (%) | |
| Prolonged aPTT | 55 (53) |
| Autoimmune disorder | 39 (37) |
| Family history for thrombosis | 4 (4) |
| Migraine | 2 (2) |
| Autoimmune disorders, no. (%) | |
| SLE | 14 (13) |
| Other | 35 (34) |
| Risk for arterial thrombosis* no. (%) | 34 (33) |
| Risk for venous thrombosis† no. (%) | 30 (29) |
| Characteristics . | Value . |
|---|---|
| No. | 104 |
| Age, y (mean ± SD) | 45 ± 15 |
| Female, no. (%) | 82 (79) |
| IgG isotype, no. (%) | 86 (83) |
| dRVVT mixing (mean ± SD) | 1.78 ± 0.5 |
| IgG aCL, GPL units (mean ± SD) | 102 ± 91 |
| IgG aβ2GPI, units (mean ± SD) | 123 ± 154 |
| IgM isotype, no. (%) | |
| dRVVT mixing | 18 (17) |
| IgM aCL, GPL units (mean ± SD) | 1.42 ± 0.3 |
| IgM aβ2GPI, units (mean ± SD) | 81 ± 58 |
| Reason for initial testing, no. (%) | |
| Prolonged aPTT | 55 (53) |
| Autoimmune disorder | 39 (37) |
| Family history for thrombosis | 4 (4) |
| Migraine | 2 (2) |
| Autoimmune disorders, no. (%) | |
| SLE | 14 (13) |
| Other | 35 (34) |
| Risk for arterial thrombosis* no. (%) | 34 (33) |
| Risk for venous thrombosis† no. (%) | 30 (29) |
dRVVT indicates diluted Russell viper venom time; and aPTT, activated partial thromboplastin time.
Considered risk factors for arterial thrombosis: diabetes mellitus, hypertension, hypercholesterolemia, obesity, smoking habit, and family history.
Considered risk factor for venous thrombosis: recent surgical intervention, perioperative immobilization, oral estroprogestinic treatment, pregnancy, malignancy, family history, thrombophilia, and previous VTE.