Comparison of cytogenetic detection rate between MC and MC cytogenetics combined with SNA-A karyotyping
| Disease group/MC . | n (%) . | MC + SNP-A . | n (%) . | P* . |
|---|---|---|---|---|
| MDS (n = 250) | ||||
| NI† | 17 (7) | Normal | 65 (26) | |
| Normal | 118 (47) | Abnormal | 70 (28) | < .0001 |
| Abnormal | 115 (46) | No additional | 47 (19) | |
| Abnormal | Additional | 68 (27) | ||
| MDS/MPN (n = 95) | ||||
| NI† | 4 (4) | Normal | 24 (25) | |
| Normal | 55 (58) | Abnormal | 35 (37) | < .0001 |
| Abnormal | 36 (38) | No additional | 10 (11) | |
| Abnormal | Additional | 26 (27) | ||
| AML (n = 85)‡ | ||||
| NI† | 7 (8) | Normal | 22 (26) | |
| Normal | 40 (47) | Abnormal | 25 (29) | .0002 |
| Abnormal | 38 (45) | No additional | 15 (18) | |
| Abnormal | Additional | 23 (27) |
| Disease group/MC . | n (%) . | MC + SNP-A . | n (%) . | P* . |
|---|---|---|---|---|
| MDS (n = 250) | ||||
| NI† | 17 (7) | Normal | 65 (26) | |
| Normal | 118 (47) | Abnormal | 70 (28) | < .0001 |
| Abnormal | 115 (46) | No additional | 47 (19) | |
| Abnormal | Additional | 68 (27) | ||
| MDS/MPN (n = 95) | ||||
| NI† | 4 (4) | Normal | 24 (25) | |
| Normal | 55 (58) | Abnormal | 35 (37) | < .0001 |
| Abnormal | 36 (38) | No additional | 10 (11) | |
| Abnormal | Additional | 26 (27) | ||
| AML (n = 85)‡ | ||||
| NI† | 7 (8) | Normal | 22 (26) | |
| Normal | 40 (47) | Abnormal | 25 (29) | .0002 |
| Abnormal | 38 (45) | No additional | 15 (18) | |
| Abnormal | Additional | 23 (27) |
NI indicates noninformative.
Comparison of cytogenetic detection rate between MC and MC + SNP-A.
Noninformative, defined as no growth by metaphase cytogenetics.
MC results not available (AML = 1 but FISH results were available. The test showed normal findings in all tested loci for del20q, del5/del5q, del7, del7q, +8).