Patient and iPS cell characteristics
Patient . | IDUA mutations . | Sex . | Age at HCT, y . | Time after HCT, y . | Donor cells . | No. of iPS colonies per 100 000 cells . |
---|---|---|---|---|---|---|
P1 | Y167X | Male | 1.1 | 0.2 | KC | 2 |
W402X | ||||||
P2 | W402X | Male | 1.8 | 0.8 | KC | 14 |
W402X | MSC | 4 |
Patient . | IDUA mutations . | Sex . | Age at HCT, y . | Time after HCT, y . | Donor cells . | No. of iPS colonies per 100 000 cells . |
---|---|---|---|---|---|---|
P1 | Y167X | Male | 1.1 | 0.2 | KC | 2 |
W402X | ||||||
P2 | W402X | Male | 1.8 | 0.8 | KC | 14 |
W402X | MSC | 4 |
iPS indicates induced pluripotent stem; IDUA, iduronidase gene; HCT, hematopoietic cell transplantation; P, patient; Y, tyrosine; X, unknown amino acid; KC, keratinocytes; W, tryptophan; and MSC, mesenchymal stromal cells.