QOL scores for cohort members at enrollment according to NIH chronic GVHD severity
| . | All (N = 298) . | Mild (n = 31) . | Moderate (n = 175) . | Severe (n = 92) . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | |
| SF-36* | ||||||||||||
| Physical-functioning scale | 256 | 42.3 (14.9-57.0) | 26 | 46.5 (23.4-57.0) | 151 | 42.3 (17.0-57.0) | 79 | 38.1 (14.9-57.0) | ||||
| Role-functioning physical scale | 259 | 37.3 (17.7-56.9) | 26 | 44.6 (17.7-56.9) | 153 | 37.3 (17.7-56.9) | 80 | 32.4 (17.7-56.9) | ||||
| Bodily pain scale | 259 | 46.1 (19.9-62.1) | 26 | 46.1 (24.9-62.1) | 152 | 46.1 (24.1-62.1) | 81 | 41.4 (19.9-62.1) | ||||
| General health perceptions scale | 259 | 41.0 (18.6-63.9) | 26 | 46.5 (28.1-63.9) | 152 | 41.0 (18.6-62.5) | 81 | 37.7 (23.4-62.5) | ||||
| Vitality scale | 260 | 45.8 (20.9-70.8) | 26 | 50.5 (30.2-64.6) | 153 | 45.8 (20.9-70.8) | 81 | 45.8 (20.9-70.8) | ||||
| Social-functioning scale | 260 | 40.5 (13.2-56.8) | 26 | 45.9 (13.2-56.8) | 153 | 40.5 (13.2-56.8) | 81 | 35.0 (13.2-56.8) | ||||
| Role-functioning emotional scale | 259 | 48.1 (9.2-55.9) | 26 | 52.0 (28.7-55.9) | 153 | 48.1 (9.2-55.9) | 80 | 44.2 (9.2-55.9) | ||||
| Mental health scale | 260 | 52.8 (13.4-64.1) | 26 | 54.2 (30.3-64.1) | 153 | 52.8 (13.4-64.1) | 81 | 50.0 (21.8-64.1) | ||||
| Physical component score | 254 | 39.2 (15.9-59.4) | 26 | 43.2 (19.9-59.3) | 149 | 40.2 (15.9-59.4) | 79 | 36.3 (19.3-56.7) | ||||
| Mental component score | 254 | 51.0 (15.3-68.4) | 26 | 53.8 (28.5-61.4) | 149 | 51.4 (17.0-68.4) | 79 | 48.1 (15.3-65.8) | ||||
| FACT-BMT | ||||||||||||
| Physical well-being | 259 | 22.0 (4.0-28.0) | 26 | 24.0 (9.0-28.0) | 152 | 22.5 (4.0-28.0) | 81 | 19.0 (7.0-28.0) | ||||
| Social/family well-being | 259 | 23.3 (0-28.0) | 26 | 24.0 (11.0-28.0) | 152 | 24.0 (0-28.0) | 81 | 23.0 (6.0-28.0) | ||||
| Emotional well-being | 258 | 20.0 (6.0-24.0) | 26 | 20.5 (14.0-24.0) | 151 | 20.0 (6.0-24.0) | 81 | 19.0 (6.0-24.0) | ||||
| Functional well-being | 258 | 17.0 (3.0-28.0) | 26 | 17.0 (7.0-28.0) | 152 | 18.0 (5.0-28.0) | 80 | 15.0 (3.0-28.0) | ||||
| BMT subscale | 258 | 27.6 (11.0-39.0) | 26 | 29.0 (14.0-36.0) | 152 | 28.0 (11.0-39.0) | 80 | 26.0 (11.1-38.9) | ||||
| FACT total | 257 | 81.0 (29.0-107.0) | 26 | 84.5 (55.0-107.0) | 151 | 84.1 (29.0-104.0) | 80 | 73.4 (37.0-105.0) | ||||
| FACT trial outcome index | 258 | 65.0 (22.0-92.0) | 26 | 70.0 (38.0-91.0) | 152 | 67.8 (22.0-92.0) | 80 | 58.5 (25.0-89.9) | ||||
| FACT-BMT total | 257 | 109.0 (48.1-142.0) | 26 | 114.0 (69.0-142.0) | 151 | 111.0 (49.0-140.0) | 80 | 98.7 (48.1-136.0) | ||||
| . | All (N = 298) . | Mild (n = 31) . | Moderate (n = 175) . | Severe (n = 92) . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | n (%) . | n . | Median (range) . | |
| SF-36* | ||||||||||||
| Physical-functioning scale | 256 | 42.3 (14.9-57.0) | 26 | 46.5 (23.4-57.0) | 151 | 42.3 (17.0-57.0) | 79 | 38.1 (14.9-57.0) | ||||
| Role-functioning physical scale | 259 | 37.3 (17.7-56.9) | 26 | 44.6 (17.7-56.9) | 153 | 37.3 (17.7-56.9) | 80 | 32.4 (17.7-56.9) | ||||
| Bodily pain scale | 259 | 46.1 (19.9-62.1) | 26 | 46.1 (24.9-62.1) | 152 | 46.1 (24.1-62.1) | 81 | 41.4 (19.9-62.1) | ||||
| General health perceptions scale | 259 | 41.0 (18.6-63.9) | 26 | 46.5 (28.1-63.9) | 152 | 41.0 (18.6-62.5) | 81 | 37.7 (23.4-62.5) | ||||
| Vitality scale | 260 | 45.8 (20.9-70.8) | 26 | 50.5 (30.2-64.6) | 153 | 45.8 (20.9-70.8) | 81 | 45.8 (20.9-70.8) | ||||
| Social-functioning scale | 260 | 40.5 (13.2-56.8) | 26 | 45.9 (13.2-56.8) | 153 | 40.5 (13.2-56.8) | 81 | 35.0 (13.2-56.8) | ||||
| Role-functioning emotional scale | 259 | 48.1 (9.2-55.9) | 26 | 52.0 (28.7-55.9) | 153 | 48.1 (9.2-55.9) | 80 | 44.2 (9.2-55.9) | ||||
| Mental health scale | 260 | 52.8 (13.4-64.1) | 26 | 54.2 (30.3-64.1) | 153 | 52.8 (13.4-64.1) | 81 | 50.0 (21.8-64.1) | ||||
| Physical component score | 254 | 39.2 (15.9-59.4) | 26 | 43.2 (19.9-59.3) | 149 | 40.2 (15.9-59.4) | 79 | 36.3 (19.3-56.7) | ||||
| Mental component score | 254 | 51.0 (15.3-68.4) | 26 | 53.8 (28.5-61.4) | 149 | 51.4 (17.0-68.4) | 79 | 48.1 (15.3-65.8) | ||||
| FACT-BMT | ||||||||||||
| Physical well-being | 259 | 22.0 (4.0-28.0) | 26 | 24.0 (9.0-28.0) | 152 | 22.5 (4.0-28.0) | 81 | 19.0 (7.0-28.0) | ||||
| Social/family well-being | 259 | 23.3 (0-28.0) | 26 | 24.0 (11.0-28.0) | 152 | 24.0 (0-28.0) | 81 | 23.0 (6.0-28.0) | ||||
| Emotional well-being | 258 | 20.0 (6.0-24.0) | 26 | 20.5 (14.0-24.0) | 151 | 20.0 (6.0-24.0) | 81 | 19.0 (6.0-24.0) | ||||
| Functional well-being | 258 | 17.0 (3.0-28.0) | 26 | 17.0 (7.0-28.0) | 152 | 18.0 (5.0-28.0) | 80 | 15.0 (3.0-28.0) | ||||
| BMT subscale | 258 | 27.6 (11.0-39.0) | 26 | 29.0 (14.0-36.0) | 152 | 28.0 (11.0-39.0) | 80 | 26.0 (11.1-38.9) | ||||
| FACT total | 257 | 81.0 (29.0-107.0) | 26 | 84.5 (55.0-107.0) | 151 | 84.1 (29.0-104.0) | 80 | 73.4 (37.0-105.0) | ||||
| FACT trial outcome index | 258 | 65.0 (22.0-92.0) | 26 | 70.0 (38.0-91.0) | 152 | 67.8 (22.0-92.0) | 80 | 58.5 (25.0-89.9) | ||||
| FACT-BMT total | 257 | 109.0 (48.1-142.0) | 26 | 114.0 (69.0-142.0) | 151 | 111.0 (49.0-140.0) | 80 | 98.7 (48.1-136.0) | ||||
QOL indicates quality of life.
Norm-based scores (mean = 50, SD = 10 based on 1998 general US population).