Comparison of transposon integration sites in normal and malignant T cells
| . | Obs/Exp* . | χ2 . | P . | Obs/Exp* . | χ2 . | P . |
|---|---|---|---|---|---|---|
| Vav-SB control data (7099 events) | CD4-SB control data (11 180 events) | |||||
| Vav-SB CIS regions (81 832 TA sites) | 10/6 | 0.563 | ns | 8/6 | 0.071 | ns |
| CD4-SB CIS regions (191 922 TA sites) | 19/15 | 0.265 | ns | 14/15 | 0.035 | ns |
| Vav-SB tumor data (2843 events) | CD4-SB tumor data (4447 events) | |||||
| VavSB CIS regions (81 832 TA sites) | 249/1 | 255.3 | < .0001 | 91/2 | 84.15 | < .0001 |
| CD4-SB CIS regions (191 922 TA sites) | 64/3 | 60.26 | < .0001 | 296/5 | 289.2 | < .0001 |
| . | Obs/Exp* . | χ2 . | P . | Obs/Exp* . | χ2 . | P . |
|---|---|---|---|---|---|---|
| Vav-SB control data (7099 events) | CD4-SB control data (11 180 events) | |||||
| Vav-SB CIS regions (81 832 TA sites) | 10/6 | 0.563 | ns | 8/6 | 0.071 | ns |
| CD4-SB CIS regions (191 922 TA sites) | 19/15 | 0.265 | ns | 14/15 | 0.035 | ns |
| Vav-SB tumor data (2843 events) | CD4-SB tumor data (4447 events) | |||||
| VavSB CIS regions (81 832 TA sites) | 249/1 | 255.3 | < .0001 | 91/2 | 84.15 | < .0001 |
| CD4-SB CIS regions (191 922 TA sites) | 64/3 | 60.26 | < .0001 | 296/5 | 289.2 | < .0001 |
Obs/Exp indicates no. of observed and expected insertion events; CIS, common insertion site; TA, potential SB insertion sites; and ns, not significant.
Calculation of expected insertion number is based on a total of 162 687 182 TA sites within the mouse reference genome.