Table 2 Candidate target genes related... | American Society of Hematology

Table 2

Candidate target genes related to the HSC/HPC function

Fold enrichment over input (log₂)	Fold difference HOXB4/control (log₂)	Gene symbol	Gene name
3.05	2.861	Tgfb1	Transforming growth factor-β1
3	−1.365	Gfi1	Growth factor independent 1
2.8	4.071	Notch 2	Notch gene homolog 2 (Drosophila)
2.67	2.846	Men 1	Multiple endocrine neoplasia 1
2.54	1.972	E2f4	E2F transcription factor 4
2.42	1.906	Gata 2	GATA binding protein 2
2.39	1.723	E2f1	E2F transcription factor 1
2.35	0.281	Runx 1	Runt-related transcription factor 1
2.3	5.261	Tle1	Transducin-like enhancer of split 1, homolog of Drosophila E(spl)
2.29	2.197	Cebpa	CCAAT/enhancer binding protein (C/EBP), α
2.27	3.204	Myc	Myelocytomatosis oncogene
2.22	5.874	Sox4	SRY-box containing gene 4
2.17	2.503	Tal1/Scl	T-cell acute lymphocytic leukemia 1
2.02	13.147	Dnmt3b	DNA methyltransferase 3B
1.97	3.529	Lmo2	LIM domain only 2 (rhombotin-like 1)
1.83	−4.55	Sfpi1	SFFV proviral integration 1
1.75	23.626	Nov	Nephroblastoma overexpressed gene
1.69	2.706	Meis1	Meis homeobox 1
1.62	4.836	Cd34	CD34 antigen
1.24	2.867	Pbx3	Pre-B-cell leukemia transcription factor 3
1.03	1.606	Pbx1	Pre-B-cell leukemia transcription factor 1
0.92	6.695	Erg	Avian erythroblastosis virus E-26 (v-ets) oncogene related
0.85	−1.78	Cdx4	Caudal-type homeo box 4
0.84	4.508	Hemgn	Hemogen
0.47	−5.725	Ahr	Arylhydrocarbon receptor

Fold enrichment over input (log₂)	Fold difference HOXB4/control (log₂)	Gene symbol	Gene name
3.05	2.861	Tgfb1	Transforming growth factor-β1
3	−1.365	Gfi1	Growth factor independent 1
2.8	4.071	Notch 2	Notch gene homolog 2 (Drosophila)
2.67	2.846	Men 1	Multiple endocrine neoplasia 1
2.54	1.972	E2f4	E2F transcription factor 4
2.42	1.906	Gata 2	GATA binding protein 2
2.39	1.723	E2f1	E2F transcription factor 1
2.35	0.281	Runx 1	Runt-related transcription factor 1
2.3	5.261	Tle1	Transducin-like enhancer of split 1, homolog of Drosophila E(spl)
2.29	2.197	Cebpa	CCAAT/enhancer binding protein (C/EBP), α
2.27	3.204	Myc	Myelocytomatosis oncogene
2.22	5.874	Sox4	SRY-box containing gene 4
2.17	2.503	Tal1/Scl	T-cell acute lymphocytic leukemia 1
2.02	13.147	Dnmt3b	DNA methyltransferase 3B
1.97	3.529	Lmo2	LIM domain only 2 (rhombotin-like 1)
1.83	−4.55	Sfpi1	SFFV proviral integration 1
1.75	23.626	Nov	Nephroblastoma overexpressed gene
1.69	2.706	Meis1	Meis homeobox 1
1.62	4.836	Cd34	CD34 antigen
1.24	2.867	Pbx3	Pre-B-cell leukemia transcription factor 3
1.03	1.606	Pbx1	Pre-B-cell leukemia transcription factor 1
0.92	6.695	Erg	Avian erythroblastosis virus E-26 (v-ets) oncogene related
0.85	−1.78	Cdx4	Caudal-type homeo box 4
0.84	4.508	Hemgn	Hemogen
0.47	−5.725	Ahr	Arylhydrocarbon receptor