Table 2

Induction of HSPC mobilization in WT versus Cnr2−/− mice after LPS administration

PB progenitorPB-HSPC/WTPB-HSPC/Cnr2−/−
Vehicle 5 ± 1 8 ± 2 
LPS 40 ± 7* 18 ± 4 
PB progenitorPB-HSPC/WTPB-HSPC/Cnr2−/−
Vehicle 5 ± 1 8 ± 2 
LPS 40 ± 7* 18 ± 4 

LPS was injected intraperitoneally at a dose of 2 pg/kg. Mice were killed 5 days after injection of LPS, and the incidence of PB-HSPC was evaluated using colony-formation assay. These are representative experiments of duplicate experiments involving 5 mice per treatment group.

*

P < .01 vs control.

P < .05 vs LPS alone.

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