Table 5 Distribution in CAD-free and CAD... | American Society of Hematology

Table 5

Distribution in CAD-free and CAD groups, FVIII:c levels, and lipid levels according to LRP1 −25C/G polymorphism (data available for 963 subjects)

	CAD-free (n = 280), %	CAD (n = 683), %	P	FVIII:c, IU/dL	P	Total cholesterol, mM	P	LDL cholesterol, mM	P	HDL cholesterol, mM	P	Total cholesterol/HDL ratio	P	Triglycerides, mM	P
LRP1 −25C/G
CC (n = 773)	83.2	79.1		165 ± 53		5.71 ± 1.13		3.79 ± 0.99		1.28 ± 0.36		4.80 ± 1.52		1.85 ± 1.13
CG (n = 174)	16.1	18.9	.180*	163 ± 52	.295†	5.60 ± 1.06	.038†	3.70 ± 0.95	.049†	1.25 ± 0.33	.577†	4.80 ± 1.81	.495†	1.76 ± 0.80	.555†
GG (n = 16)	0.7	2.0		185 ± 65		5.05 ± 0.61		3.16 ± 0.52		1.25 ± 0.33		4.28 ± 1.11		1.67 ± 0.53
Carrrier G (vs CC)	16.8	20.9	.142*	165 ± 53	.981‡	5.55 ± 1.04	.079‡	3.66 ± 0.93	.121‡	1.25 ± 0.33	.294‡	4.75 ± 1.76	.756‡	1.75 ± 0.78	.299‡
Carrrier C (vs GG)	99.3	98.0	.141*	165 ± 53	.130‡	5.69 ± 1.12	.024‡	3.77 ± 0.98	.025‡	1.27 ± 0.35	.797‡	4.80 ± 1.58	.235‡	1.83 ± 1.08	.566‡

	CAD-free (n = 280), %	CAD (n = 683), %	P	FVIII:c, IU/dL	P	Total cholesterol, mM	P	LDL cholesterol, mM	P	HDL cholesterol, mM	P	Total cholesterol/HDL ratio	P	Triglycerides, mM	P
LRP1 −25C/G
CC (n = 773)	83.2	79.1		165 ± 53		5.71 ± 1.13		3.79 ± 0.99		1.28 ± 0.36		4.80 ± 1.52		1.85 ± 1.13
CG (n = 174)	16.1	18.9	.180*	163 ± 52	.295†	5.60 ± 1.06	.038†	3.70 ± 0.95	.049†	1.25 ± 0.33	.577†	4.80 ± 1.81	.495†	1.76 ± 0.80	.555†
GG (n = 16)	0.7	2.0		185 ± 65		5.05 ± 0.61		3.16 ± 0.52		1.25 ± 0.33		4.28 ± 1.11		1.67 ± 0.53
Carrrier G (vs CC)	16.8	20.9	.142*	165 ± 53	.981‡	5.55 ± 1.04	.079‡	3.66 ± 0.93	.121‡	1.25 ± 0.33	.294‡	4.75 ± 1.76	.756‡	1.75 ± 0.78	.299‡
Carrrier C (vs GG)	99.3	98.0	.141*	165 ± 53	.130‡	5.69 ± 1.12	.024‡	3.77 ± 0.98	.025‡	1.27 ± 0.35	.797‡	4.80 ± 1.58	.235‡	1.83 ± 1.08	.566‡

By χ² test.

By analysis of variance.

By t test.