Outcome of therapy in elderly patients with AML
. | Control group . | G-PBSC group . | P . |
---|---|---|---|
Complete remission rates | |||
After the first induction, n/N | 8/28 | 19/30 | .006 |
After the second induction, n/N | 12/28 | 24/30 | .006 |
Patients >70 y, n/N | 1/8 | 13/14 | .0003 |
Patients <70 y, n/N | 11/20 | 11/16 | .4 |
In high-risk category, n/N | 4/13 | 7/12 | .23 |
In standard-risk category, n/N | 8/15 | 17/18 | .01 |
Disease resistance, n/N | 11/28 | 3/30 | .01 |
Early death rate, n/N | 4/28 | 2/30 | .69 |
Median time of ANC > 0.5 × 109/L, d | |||
After the first induction | 16 | 11 | .02 |
After the post-remission | 12.5 | 10 | .06 |
Median time of platelet count > 30 × 109/L, d | |||
After the first induction | 20 | 14.5 | .02 |
After the post-remission | 17 | 14 | .06 |
Severe infection | |||
After the first induction, n/N | 16/28 | 8/30 | .02 |
After the post-remission, n/N | 4/12 | 5/24 | .44 |
. | Control group . | G-PBSC group . | P . |
---|---|---|---|
Complete remission rates | |||
After the first induction, n/N | 8/28 | 19/30 | .006 |
After the second induction, n/N | 12/28 | 24/30 | .006 |
Patients >70 y, n/N | 1/8 | 13/14 | .0003 |
Patients <70 y, n/N | 11/20 | 11/16 | .4 |
In high-risk category, n/N | 4/13 | 7/12 | .23 |
In standard-risk category, n/N | 8/15 | 17/18 | .01 |
Disease resistance, n/N | 11/28 | 3/30 | .01 |
Early death rate, n/N | 4/28 | 2/30 | .69 |
Median time of ANC > 0.5 × 109/L, d | |||
After the first induction | 16 | 11 | .02 |
After the post-remission | 12.5 | 10 | .06 |
Median time of platelet count > 30 × 109/L, d | |||
After the first induction | 20 | 14.5 | .02 |
After the post-remission | 17 | 14 | .06 |
Severe infection | |||
After the first induction, n/N | 16/28 | 8/30 | .02 |
After the post-remission, n/N | 4/12 | 5/24 | .44 |