Crude incidence and incidence rate ratios for BL among persons with AIDS in the United States, 1980-2005
| Characteristics . | No. of subjects (%) . | No. of incident BL cases . | Crude incidence rate, per 100 000 person-years . | Crude incidence rate ratios (95% CI) . | Adjusted incidence rate ratios (95% CI)* . |
|---|---|---|---|---|---|
| Overall | 567 865 (100) | 306 | 22.0 | ||
| Sex | |||||
| Male | 456 635 (80.4) | 273 | 24.4 | 2.0 (1.4-2.9) | 1.6 (1.1-2.3) |
| Female | 111 230 (19.6) | 33 | 12.2 | 1 | 1 |
| Race/ethnicity | |||||
| Non-Hispanic white | 218 917 (38.5) | 168 | 30.1 | 1 | 1 |
| Non-Hispanic black | 235 578 (41.5) | 54 | 9.6 | 0.3 (0.2-0.4) | 0.4 (0.3-0.5) |
| Hispanic | 113 370 (20.0) | 84 | 30.9 | 1.0 (0.8-1.3) | 1.2 (0.9-1.5) |
| Mode of HIV transmission | |||||
| MSM | 281 365 (49.6) | 190 | 26.4 | 1 | 1 |
| IDU | 137 533 (24.2) | 49 | 15.5 | 0.6 (0.4-0.8) | 0.7 (0.5-1.0) |
| Heterosexual | 70 283 (12.4) | 23 | 12.7 | 0.5 (0.3- 0.7) | 0.7 (0.5-1.1) |
| Other/unknown | 78 633 (13.9) | 44 | 25.1 | 1.0 (0.7-1.3) | 1.2 (0.8-1.8) |
| Age at AIDS-onset, y | |||||
| 0-19 | 9339 (1.6) | 10 | 39.5 | 1.6 (0.8-3.0) | 2.3 (1.2-4.4) |
| 20-31 | 129 139 (22.7) | 49 | 14.2 | 0.6 (0.4-0.8) | 0.6 (0.4-0.8) |
| 32-39 | 200 765 (35.4) | 125 | 24.7 | 1 | 1 |
| 40-51 | 175 019 (30.8) | 99 | 24.2 | 1.0 (0.8-1.3) | 1.0 (0.8-1.3) |
| 52-59 | 35 450 (6.2) | 13 | 17.9 | 0.7 (0.4-1.3) | 0.8 (0.4-1.4) |
| 60 or older | 18 153 (3.2) | 10 | 31.7 | 1.3 (0.7-2.4) | 1.4 (0.7-2.7) |
| CD4 lymphocyte count/μL† | |||||
| 0-49 | 108 512 (31.4) | 23 | 9.6 | 0.3 (0.2-0.5) | 0.3 (0.2-0.6) |
| 50-149 | 111 304 (32.2) | 90 | 29.8 | 1.0 (0.7-1.5) | 1.0 (0.7-1.5) |
| 150-249 | 91 315 (24.4) | 67 | 23.9 | 0.8 (0.5-1.2) | 0.8 (0.5-1.2) |
| 250+ | 34 183 (9.8) | 33 | 30.7 | 1 | 1 |
| Missing‡ | 120 902 (25.9) | 36 | 13.6 | ||
| Calendar year of AIDS onset | |||||
| 1980-1989 | 101 649 (17.9) | 57 | 29.4 | 1.3 (1.0-1.8) | 1.6 (1.1-2.4) |
| 1990-1995 | 247 922 (43.7) | 146 | 22.5 | 1 | 1 |
| 1996-2005 | 218 294 (38.4) | 103 | 18.8 | 0.8 (0.6-1.1) | 0.9 (0.7-1.1) |
| Characteristics . | No. of subjects (%) . | No. of incident BL cases . | Crude incidence rate, per 100 000 person-years . | Crude incidence rate ratios (95% CI) . | Adjusted incidence rate ratios (95% CI)* . |
|---|---|---|---|---|---|
| Overall | 567 865 (100) | 306 | 22.0 | ||
| Sex | |||||
| Male | 456 635 (80.4) | 273 | 24.4 | 2.0 (1.4-2.9) | 1.6 (1.1-2.3) |
| Female | 111 230 (19.6) | 33 | 12.2 | 1 | 1 |
| Race/ethnicity | |||||
| Non-Hispanic white | 218 917 (38.5) | 168 | 30.1 | 1 | 1 |
| Non-Hispanic black | 235 578 (41.5) | 54 | 9.6 | 0.3 (0.2-0.4) | 0.4 (0.3-0.5) |
| Hispanic | 113 370 (20.0) | 84 | 30.9 | 1.0 (0.8-1.3) | 1.2 (0.9-1.5) |
| Mode of HIV transmission | |||||
| MSM | 281 365 (49.6) | 190 | 26.4 | 1 | 1 |
| IDU | 137 533 (24.2) | 49 | 15.5 | 0.6 (0.4-0.8) | 0.7 (0.5-1.0) |
| Heterosexual | 70 283 (12.4) | 23 | 12.7 | 0.5 (0.3- 0.7) | 0.7 (0.5-1.1) |
| Other/unknown | 78 633 (13.9) | 44 | 25.1 | 1.0 (0.7-1.3) | 1.2 (0.8-1.8) |
| Age at AIDS-onset, y | |||||
| 0-19 | 9339 (1.6) | 10 | 39.5 | 1.6 (0.8-3.0) | 2.3 (1.2-4.4) |
| 20-31 | 129 139 (22.7) | 49 | 14.2 | 0.6 (0.4-0.8) | 0.6 (0.4-0.8) |
| 32-39 | 200 765 (35.4) | 125 | 24.7 | 1 | 1 |
| 40-51 | 175 019 (30.8) | 99 | 24.2 | 1.0 (0.8-1.3) | 1.0 (0.8-1.3) |
| 52-59 | 35 450 (6.2) | 13 | 17.9 | 0.7 (0.4-1.3) | 0.8 (0.4-1.4) |
| 60 or older | 18 153 (3.2) | 10 | 31.7 | 1.3 (0.7-2.4) | 1.4 (0.7-2.7) |
| CD4 lymphocyte count/μL† | |||||
| 0-49 | 108 512 (31.4) | 23 | 9.6 | 0.3 (0.2-0.5) | 0.3 (0.2-0.6) |
| 50-149 | 111 304 (32.2) | 90 | 29.8 | 1.0 (0.7-1.5) | 1.0 (0.7-1.5) |
| 150-249 | 91 315 (24.4) | 67 | 23.9 | 0.8 (0.5-1.2) | 0.8 (0.5-1.2) |
| 250+ | 34 183 (9.8) | 33 | 30.7 | 1 | 1 |
| Missing‡ | 120 902 (25.9) | 36 | 13.6 | ||
| Calendar year of AIDS onset | |||||
| 1980-1989 | 101 649 (17.9) | 57 | 29.4 | 1.3 (1.0-1.8) | 1.6 (1.1-2.4) |
| 1990-1995 | 247 922 (43.7) | 146 | 22.5 | 1 | 1 |
| 1996-2005 | 218 294 (38.4) | 103 | 18.8 | 0.8 (0.6-1.1) | 0.9 (0.7-1.1) |
BL indicates Burkitt lymphoma; CI, confidence interval; MSM, men who have sex with men; and IDU, intravenous drug users.
Incidence rate ratio for BL for each factor is adjusted for all other factors in the table; records with missing CD4 data were coded as missing and included in the model.
CD4 lymphocyte count analyses based on data from 1990-2005.
Percentage of the CD4 lymphocyte counts for “missing” are of the total; for known categories, the percentages are based on those with known CD4 lymphocyte counts.