Characteristics of participants according to coumarin use
| Variable . | Coumarin, N = 19 . | No coumarin, N = 18 . | P* . |
|---|---|---|---|
| Sex, male/female | 15/4 | 9/9 | .065 |
| Age, y (range) | 48 (33-56) | 46 (36-53) | .213 |
| (Ever) smoking, % | 68 | 50 | .254 |
| Body mass index, kg/m2 | 29 (± 5) | 25 (± 4) | .015 |
| Systolic blood pressure, mmHg | 128 (± 13) | 125 (± 19) | .592 |
| Diastolic blood pressure, mmHg | 81 (± 8) | 80 (± 14) | .676 |
| Glucose, mmol/L (range) | 5.1 (4.3-9.0) | 4.9 (4.2-6.2) | .807 |
| Total cholesterol, mmol/L | 5.9 (± 1.2) | 5.5 (± 1.1) | .303 |
| HDL cholesterol, mmol/L | 1.18 (± 0.3) | 1.40 (± 0.4) | .058 |
| LDL cholesterol, mmol/L | 4.1 (± 0.8) | 3.7 (± 0.9) | .173 |
| Triglycerides, mmol/l | 1.57 (± 0.9) | 0.98 (± 0.6) | .023 |
| Creatinine, μmol/L | 81 (± 11.5) | 79 (± 16.4) | .577 |
| Estimated creatinine clearance, mL/min | 120 (± 27) | 105 (± 24) | .077 |
| Median calcium-phosphate product (range) | 2.3 (1.5-4.4) | 2.6 (2.3-3.4) | .104 |
| Variable . | Coumarin, N = 19 . | No coumarin, N = 18 . | P* . |
|---|---|---|---|
| Sex, male/female | 15/4 | 9/9 | .065 |
| Age, y (range) | 48 (33-56) | 46 (36-53) | .213 |
| (Ever) smoking, % | 68 | 50 | .254 |
| Body mass index, kg/m2 | 29 (± 5) | 25 (± 4) | .015 |
| Systolic blood pressure, mmHg | 128 (± 13) | 125 (± 19) | .592 |
| Diastolic blood pressure, mmHg | 81 (± 8) | 80 (± 14) | .676 |
| Glucose, mmol/L (range) | 5.1 (4.3-9.0) | 4.9 (4.2-6.2) | .807 |
| Total cholesterol, mmol/L | 5.9 (± 1.2) | 5.5 (± 1.1) | .303 |
| HDL cholesterol, mmol/L | 1.18 (± 0.3) | 1.40 (± 0.4) | .058 |
| LDL cholesterol, mmol/L | 4.1 (± 0.8) | 3.7 (± 0.9) | .173 |
| Triglycerides, mmol/l | 1.57 (± 0.9) | 0.98 (± 0.6) | .023 |
| Creatinine, μmol/L | 81 (± 11.5) | 79 (± 16.4) | .577 |
| Estimated creatinine clearance, mL/min | 120 (± 27) | 105 (± 24) | .077 |
| Median calcium-phosphate product (range) | 2.3 (1.5-4.4) | 2.6 (2.3-3.4) | .104 |
HDL indicates high-density lipoprotein; and LDL, low-density lipoprotein.
P values shown in bold indicate a significant difference.
The χ 2 test was used for dichotomous variables, the Student t test for normally distributed values, and the Mann-Whitney U test for not normally distributed variables.