Table 5

HRs and 95% CIs for selected arterial and venous thromboses among MGUS patients versus matched controls, stratified by M-protein concentration at diagnosis

Type of thrombosisConcentration of M-protein less than 10 g/L
Concentration of M-protein more than 10 g/L
1-year follow-up
5-year follow-up
1-year follow-up
5-year follow-up
MGUS patients (n = 1732)Controls (n = 6585)HR* (95% CI)MGUS patientsControlsHR* (95% CI)MGUS patients (n = 1108)Controls (n = 4214)HR* (95% CI)MGUS patientsControlHR* (95% CI)
Arterial thrombosis 84 219 1.5 (1.2-1.9) 207 738 1.1 (0.9-1.3) 63 154 1.6 (1.2-2.1) 163 529 1.2 (1.0-1.4) 
Venous thrombosis 16 18 3.4 (1.7-6.7) 47 95 2.0 (1.4-2.8) 18 19 3.6 (1.9-6.9) 40 72 2.2 (1.5-3.2) 
Type of thrombosisConcentration of M-protein less than 10 g/L
Concentration of M-protein more than 10 g/L
1-year follow-up
5-year follow-up
1-year follow-up
5-year follow-up
MGUS patients (n = 1732)Controls (n = 6585)HR* (95% CI)MGUS patientsControlsHR* (95% CI)MGUS patients (n = 1108)Controls (n = 4214)HR* (95% CI)MGUS patientsControlHR* (95% CI)
Arterial thrombosis 84 219 1.5 (1.2-1.9) 207 738 1.1 (0.9-1.3) 63 154 1.6 (1.2-2.1) 163 529 1.2 (1.0-1.4) 
Venous thrombosis 16 18 3.4 (1.7-6.7) 47 95 2.0 (1.4-2.8) 18 19 3.6 (1.9-6.9) 40 72 2.2 (1.5-3.2) 
*

Adjusted for age, sex, and calendar period.

Angina pectoris, unstable angina, myocardial infarction, transient ischemic attack, and cerebral infarction.

DVT and PE.

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