HRs and 95% CIs for selected arterial and venous thrombosis among 18 627 MM patients versus 70 991 matched controls
| Category . | 1-year follow-up . | 5-year follow-up . | 10-year follow-up . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MM patients . | Controls . | HR* (95% CI) . | MM patients . | Controls . | HR* (95% CI) . | MM patients . | Controls . | HR* (95% CI) . | |
| Thrombosis by location | |||||||||
| DVT | 252 | 146 | 8.0 (6.5-9.9) | 459 | 581 | 5.2 (4.6-5.8) | 528 | 1035 | 4.6 (4.1-5.1) |
| PE | 152 | 97 | 7.3 (5.6-9.4) | 263 | 403 | 4.2 (4.1-5.1) | 304 | 714 | 3.8 (3.3-4.4) |
| Coronary artery disease† | 537 | 1137 | 2.2 (2.0-2.5) | 1079 | 4176 | 1.8 (1.6-1.9) | 1263 | 6756 | 1.7 (1.6-1.8) |
| Cerebrovascular‡ | 203 | 655 | 1.5 (1.3-1.8) | 475 | 2830 | 1.2 (1.1-1.3) | 601 | 4956 | 1.2 (1.1-1.3) |
| Type of thrombosis | |||||||||
| Arterial thrombosis§ | 712 | 1699 | 1.9 (1.8-2.1) | 1471 | 6413 | 1.5 (1.4-1.6) | 1751 | 10 490 | 1.5 (1.4-1.5) |
| Venous thrombosis‖ | 384 | 227 | 7.5 (6.4-8.9) | 678 | 904 | 4.6 (4.1-5.1) | 777 | 1602 | 4.1 (3.8-4.5) |
| Any thrombosis (combined) | |||||||||
| All patients | 1065 | 1892 | 2.6 (2.4-2.8) | 2039 | 7073 | 1.9 (1.8-2.0) | 2384 | 11 558 | 1.8 (1.7-1.9) |
| Males | 612 | 1163 | 2.5 (2.2-2.7) | 1156 | 4159 | 1.8 (1.7-1.9) | 1338 | 6653 | 1.8 (1.7-1.9) |
| Females | 453 | 729 | 2.8 (2.5-3.2) | 883 | 2914 | 2.0 (1.8-2.1) | 1046 | 4905 | 1.9 (1.8-2.0) |
| Category . | 1-year follow-up . | 5-year follow-up . | 10-year follow-up . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MM patients . | Controls . | HR* (95% CI) . | MM patients . | Controls . | HR* (95% CI) . | MM patients . | Controls . | HR* (95% CI) . | |
| Thrombosis by location | |||||||||
| DVT | 252 | 146 | 8.0 (6.5-9.9) | 459 | 581 | 5.2 (4.6-5.8) | 528 | 1035 | 4.6 (4.1-5.1) |
| PE | 152 | 97 | 7.3 (5.6-9.4) | 263 | 403 | 4.2 (4.1-5.1) | 304 | 714 | 3.8 (3.3-4.4) |
| Coronary artery disease† | 537 | 1137 | 2.2 (2.0-2.5) | 1079 | 4176 | 1.8 (1.6-1.9) | 1263 | 6756 | 1.7 (1.6-1.8) |
| Cerebrovascular‡ | 203 | 655 | 1.5 (1.3-1.8) | 475 | 2830 | 1.2 (1.1-1.3) | 601 | 4956 | 1.2 (1.1-1.3) |
| Type of thrombosis | |||||||||
| Arterial thrombosis§ | 712 | 1699 | 1.9 (1.8-2.1) | 1471 | 6413 | 1.5 (1.4-1.6) | 1751 | 10 490 | 1.5 (1.4-1.5) |
| Venous thrombosis‖ | 384 | 227 | 7.5 (6.4-8.9) | 678 | 904 | 4.6 (4.1-5.1) | 777 | 1602 | 4.1 (3.8-4.5) |
| Any thrombosis (combined) | |||||||||
| All patients | 1065 | 1892 | 2.6 (2.4-2.8) | 2039 | 7073 | 1.9 (1.8-2.0) | 2384 | 11 558 | 1.8 (1.7-1.9) |
| Males | 612 | 1163 | 2.5 (2.2-2.7) | 1156 | 4159 | 1.8 (1.7-1.9) | 1338 | 6653 | 1.8 (1.7-1.9) |
| Females | 453 | 729 | 2.8 (2.5-3.2) | 883 | 2914 | 2.0 (1.8-2.1) | 1046 | 4905 | 1.9 (1.8-2.0) |
Adjusted for age, sex, and calendar period at diagnosis.
Angina pectoris, unstable angina, and myocardial infarction.
Cerebral infarction, transient ischemic attack, and cerebral hemorrhage.
Angina pectoris, unstable angina, myocardial infarction, transient ischemic attack, and cerebral infarction.
DVT and PE.