Long-term splenic lymphoid reconstitution in transplanted mice
| . | CD4+, % . | CD8+, % . | B220+IgM+, % . | NK1.1+, % . |
|---|---|---|---|---|
| Transplantation experiment 1 (11-12 mo) | ||||
| Mock (n = 7) | 8.1 ± 5.3 | 0.5 ± 0.8 | 0.2 ± 0.2 | 0.1 ± 0.2 |
| MSCV-hγc (n = 4) | 12.8 ± 10.5 | 4.2 ± 2.9* | 20.6 ± 13.8* | 1.6 ± 2.8 |
| Revgen (n = 10) | 12.7 ± 5.8 | 10.2 ± 4.9* | 16.1 ± 9.2* | 1.1 ± 1.8 |
| Transplantation experiment 2 (7-8 mo) | ||||
| Mock (n = 8) | 8.4 ± 3.9 | 1.2 ± 1.2 | 0.1 ± 0.1 | 0.1 ± 0.1 |
| MSCV-hγc (n = 11) | 20.6 ± 6.2* | 13.8 ± 5.4* | 29.3 ± 12.9* | 0.6 ± 0.7* |
| EF1α (n = 8) | 16.9 ± 5.5* | 16.8 ± 7.7* | 44.4 ± 11.3* | 1.0 ± 1.1* |
| EF1α* (n = 4) | 18.1 ± 1.7* | 16.5 ± 6.3* | 30.7 ± 13.9* | 0.2 ± 0.2 |
| . | CD4+, % . | CD8+, % . | B220+IgM+, % . | NK1.1+, % . |
|---|---|---|---|---|
| Transplantation experiment 1 (11-12 mo) | ||||
| Mock (n = 7) | 8.1 ± 5.3 | 0.5 ± 0.8 | 0.2 ± 0.2 | 0.1 ± 0.2 |
| MSCV-hγc (n = 4) | 12.8 ± 10.5 | 4.2 ± 2.9* | 20.6 ± 13.8* | 1.6 ± 2.8 |
| Revgen (n = 10) | 12.7 ± 5.8 | 10.2 ± 4.9* | 16.1 ± 9.2* | 1.1 ± 1.8 |
| Transplantation experiment 2 (7-8 mo) | ||||
| Mock (n = 8) | 8.4 ± 3.9 | 1.2 ± 1.2 | 0.1 ± 0.1 | 0.1 ± 0.1 |
| MSCV-hγc (n = 11) | 20.6 ± 6.2* | 13.8 ± 5.4* | 29.3 ± 12.9* | 0.6 ± 0.7* |
| EF1α (n = 8) | 16.9 ± 5.5* | 16.8 ± 7.7* | 44.4 ± 11.3* | 1.0 ± 1.1* |
| EF1α* (n = 4) | 18.1 ± 1.7* | 16.5 ± 6.3* | 30.7 ± 13.9* | 0.2 ± 0.2 |
P < .05 versus mock (t test).