Table 2

Distribution of children with ALL within the high- and low-risk assessment group and rate of symptomatic venous thrombosis in the observational cohorts

ALL populationPilot cohort*Validation cohortP2 test)
Total number 465 of 552 339 of 347 .001 
    Score 2.5 or lower, n (%) 394 (86.4) 322 (94.9)  
    Score greater than 2.5, n (%) 62 (13.5) 17 (5.01)  
VTE onset, d, n (%) 34 (7.5) 19 (5.9) .41 
    Median (min-max) 32 (12-39) 34 (13-49)  
    Score 2.5 or lower, n (%) 11 (2.8) 8 (2.5)  
    Score greater than 2.5, n (%) 23 (37) 11 (64.7) <.001 
ALL populationPilot cohort*Validation cohortP2 test)
Total number 465 of 552 339 of 347 .001 
    Score 2.5 or lower, n (%) 394 (86.4) 322 (94.9)  
    Score greater than 2.5, n (%) 62 (13.5) 17 (5.01)  
VTE onset, d, n (%) 34 (7.5) 19 (5.9) .41 
    Median (min-max) 32 (12-39) 34 (13-49)  
    Score 2.5 or lower, n (%) 11 (2.8) 8 (2.5)  
    Score greater than 2.5, n (%) 23 (37) 11 (64.7) <.001 

ALL indicates acute lymphoblastic leukemia; and VTE, venous thromboembolism.

*

Included BFM 90/95 and COALL 92/97.

Included BFM 2000 and FRALLE 2000.

P value for score < 2.5 vs > 2.5.

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