Table 1 Serum asparaginase activity... | American Society of Hematology

Table 1

Serum asparaginase activity after a single dose of PEG-asparaginase (2500 IU/m²) given as a 1-hour intravenous infusion in children and adolescents with newly diagnosed ALL

Sample time, d	No. of patients	Serum asparaginase activity, IU/mL		Percentage of patients with asparaginase activity, IU/mL
Sample time, d	No. of patients	Median (range)	Mean ± SD	≥ 0.025	≥ 0.1	≥ 0.2
4	130	0.66 (< 0.025-2.34)	0.73 ± 0.29	96	96	96
11	133	0.48 (< 0.025-1.58)	0.49 ± 0.22	97	95	92
18	112	0.20 (< 0.025-1.24)	0.23 ± 0.14	96	88	52
25	113	0.04 (< 0.025-0.41)	0.07 ± 0.05	70	7	2

Sample time, d	No. of patients	Serum asparaginase activity, IU/mL		Percentage of patients with asparaginase activity, IU/mL
Sample time, d	No. of patients	Median (range)	Mean ± SD	≥ 0.025	≥ 0.1	≥ 0.2
4	130	0.66 (< 0.025-2.34)	0.73 ± 0.29	96	96	96
11	133	0.48 (< 0.025-1.58)	0.49 ± 0.22	97	95	92
18	112	0.20 (< 0.025-1.24)	0.23 ± 0.14	96	88	52
25	113	0.04 (< 0.025-0.41)	0.07 ± 0.05	70	7	2