Immunoglobulin variable heavy and light chain genes of 7 human MALT lymphoma cases
| Case . | VH segment . | Homology % . | Clones sequenced . | Somatic mutation . | Intraclonal variation . | JH segment . | D segment . | CDR3 length . | VL segment . | JL segment . |
|---|---|---|---|---|---|---|---|---|---|---|
| hu-1 | IGHV1-69*01 | 88.19 | 8 | + | − | IGHJ4*02 | IGHD4-17*01 | 14 | IGKV3-20*01 | IGKJ4*01 |
| hu-2 | IGHV3-7*01 | 98.61 | 6 | − | − | IGHJ3*02 | IGHD3-10*01 | 17 | IGKV1-9*01 | IGKJ4*01 |
| hu-3 | IGHV3-66*02 | 93.33 | 7 | + | + | IGHJ4*02 | IGHD3-3*01 | 14 | IGKV1-5*03 | IGKJ2*01 |
| hu-4 | IGHV1-69*01 | 94.10 | 6 | + | − | IGHJ3*02 | IGHD1-1*01 | 18 | IGKV3-20*01 | IGKJ4*01 |
| hu-5 | IGHV3-33*01 | 98.61 | 5 | − | + | IGHJ3*02 | IGHD5-24*01 | 12 | IGKV1-5*03 | IGKJ1*01 |
| hu-6 | IGHV1-69*01 | 96.88 | 6 | + | + | IGHJ5*02 | IGHD6-19*01 | 17 | IGKV3-20*01 | IGKJ4*01 |
| hu-7 | IGHV1-69*05 | 85.07 | 8 | + | − | IGHJ1*01 | IGHD4-23*01 | 15 | IGKV1-9*01 | IGKJ5*01 |
| Case . | VH segment . | Homology % . | Clones sequenced . | Somatic mutation . | Intraclonal variation . | JH segment . | D segment . | CDR3 length . | VL segment . | JL segment . |
|---|---|---|---|---|---|---|---|---|---|---|
| hu-1 | IGHV1-69*01 | 88.19 | 8 | + | − | IGHJ4*02 | IGHD4-17*01 | 14 | IGKV3-20*01 | IGKJ4*01 |
| hu-2 | IGHV3-7*01 | 98.61 | 6 | − | − | IGHJ3*02 | IGHD3-10*01 | 17 | IGKV1-9*01 | IGKJ4*01 |
| hu-3 | IGHV3-66*02 | 93.33 | 7 | + | + | IGHJ4*02 | IGHD3-3*01 | 14 | IGKV1-5*03 | IGKJ2*01 |
| hu-4 | IGHV1-69*01 | 94.10 | 6 | + | − | IGHJ3*02 | IGHD1-1*01 | 18 | IGKV3-20*01 | IGKJ4*01 |
| hu-5 | IGHV3-33*01 | 98.61 | 5 | − | + | IGHJ3*02 | IGHD5-24*01 | 12 | IGKV1-5*03 | IGKJ1*01 |
| hu-6 | IGHV1-69*01 | 96.88 | 6 | + | + | IGHJ5*02 | IGHD6-19*01 | 17 | IGKV3-20*01 | IGKJ4*01 |
| hu-7 | IGHV1-69*05 | 85.07 | 8 | + | − | IGHJ1*01 | IGHD4-23*01 | 15 | IGKV1-9*01 | IGKJ5*01 |
MALT indicates mucosa-associated lymphoid tissue; and hu, human.