Table 6

Clinical and diagnostic characteristics of patients with DS-ALL with high/medium expression of CRLF2 versus low/no expression of CRLF2

No/low CRLF2 expression (n = 20)High/medium CRLF2 expression (n = 33)P
Sex   > .999* 
    Male 11 17  
    Female 9 16  
Age, y   .004† 
    Mean (SE) 9.87 (1.21) 5.56 (0.67)  
    Median (range) 11.62 (1.74-18.7) 4.06 (1.99-20.22)  
White blood cell count at diagnosis, cells/L   .392† 
    Mean (SE) 41.6 ∗ 109 (8.7 ∗ 109) 39.8 ∗ (9.7 ∗ 109)  
    Median (range) 23.9 ∗ 109 (2.4-130 ∗ 109) 18 930 (1.5-259 ∗ 109)  
JAK2 R683 mutations   .008* 
    Yes 0 10  
    No 20 22  
No/low CRLF2 expression (n = 20)High/medium CRLF2 expression (n = 33)P
Sex   > .999* 
    Male 11 17  
    Female 9 16  
Age, y   .004† 
    Mean (SE) 9.87 (1.21) 5.56 (0.67)  
    Median (range) 11.62 (1.74-18.7) 4.06 (1.99-20.22)  
White blood cell count at diagnosis, cells/L   .392† 
    Mean (SE) 41.6 ∗ 109 (8.7 ∗ 109) 39.8 ∗ (9.7 ∗ 109)  
    Median (range) 23.9 ∗ 109 (2.4-130 ∗ 109) 18 930 (1.5-259 ∗ 109)  
JAK2 R683 mutations   .008* 
    Yes 0 10  
    No 20 22  
*

According to Fisher exact test.

†

According to Mann-Whitney U test.

View Large
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal