Blood counts are normal in BMP hypomorphs
| . | WT . | Mutant . | P . |
|---|---|---|---|
| WBCs, ×103/μL | 5.7 ± 1.1 | 9.7 ± 1.1 | .03 |
| RBCs, ×106/μL | 8.8 ± 0.2 | 9.1 ± 0.1 | .21 |
| Hemoglobin, g/dL | 14.0 ± 0.4 | 14.6 ± 0.2 | .12 |
| Hematocrit, % | 47.5 ± 1.8 | 52.5 ± 1.6 | .06 |
| MCV, fL | 53.7 ± 1.1 | 57.2 ± 1.8 | .20 |
| MCH, pg | 15.8 ± 0.1 | 16.0 ± 0.2 | .57 |
| MCHC, % | 29.5 ± 0.8 | 27.9 ± 0.7 | .21 |
| Platelets, ×103/μL | 1147 ± 37 | 1171 ± 131 | .86 |
| . | WT . | Mutant . | P . |
|---|---|---|---|
| WBCs, ×103/μL | 5.7 ± 1.1 | 9.7 ± 1.1 | .03 |
| RBCs, ×106/μL | 8.8 ± 0.2 | 9.1 ± 0.1 | .21 |
| Hemoglobin, g/dL | 14.0 ± 0.4 | 14.6 ± 0.2 | .12 |
| Hematocrit, % | 47.5 ± 1.8 | 52.5 ± 1.6 | .06 |
| MCV, fL | 53.7 ± 1.1 | 57.2 ± 1.8 | .20 |
| MCH, pg | 15.8 ± 0.1 | 16.0 ± 0.2 | .57 |
| MCHC, % | 29.5 ± 0.8 | 27.9 ± 0.7 | .21 |
| Platelets, ×103/μL | 1147 ± 37 | 1171 ± 131 | .86 |
Blood counts were assessed in 7 wild-type (WT) and 13 age-matched BMP4 hypomorphs (8-12 weeks old). Platelet counts were obtained for 5 WT and 5 BMP4 hypomorphs. All hematologic parameters measured for both genotypes were in the normal range. The mean value ± SEM is presented for each parameter. The calculated P values from unpaired, 2-tailed, Student t tests for each parameter are shown.
WBCs indicates white blood cells; RBCs, red blood cells; MCV, mean corpuscle volume; MCH, mean corpuscular hemoglobin; and MCHC, mean corpuscular hemoglobin concentration.