Cytogenetics
| Cytogenetics . | % of normal PC from all BMPC (N-PC/BMPC) . | P . | |
|---|---|---|---|
| ≤ 5% (n = 439) . | > 5% (n = 62) . | ||
| IgH translocations | 187 (43%) | 8 (13%) | < .001 |
| t(4;14) | 66 (15%) | 0 (0%) | .002 |
| t(11;14) | 79 (18%) | 8 (13%) | NS |
| t(14;16) | 18 (4%) | 0 (0%) | NS |
| Others | 35 (8%) | 0 (0%) | .009 |
| Del (13q) | 180 (41%) | 3 (5%) | < .001 |
| Del (17p) | 36 (8%) | 2 (3%) | NS |
| High-risk: any t(4;14), t(14;16), or del(17p)− | 114 (26%) | 2 (3%) | .006 |
| Cytogenetics . | % of normal PC from all BMPC (N-PC/BMPC) . | P . | |
|---|---|---|---|
| ≤ 5% (n = 439) . | > 5% (n = 62) . | ||
| IgH translocations | 187 (43%) | 8 (13%) | < .001 |
| t(4;14) | 66 (15%) | 0 (0%) | .002 |
| t(11;14) | 79 (18%) | 8 (13%) | NS |
| t(14;16) | 18 (4%) | 0 (0%) | NS |
| Others | 35 (8%) | 0 (0%) | .009 |
| Del (13q) | 180 (41%) | 3 (5%) | < .001 |
| Del (17p) | 36 (8%) | 2 (3%) | NS |
| High-risk: any t(4;14), t(14;16), or del(17p)− | 114 (26%) | 2 (3%) | .006 |
Information on patient cytogenetics corresponds to a parallel series of not uniformly treated MM patients, not to the GEM2000 series reported in the present paper.
Results expressed as percentage of cases.
NS indicates not statistically significant.