Intraclonal diversification analysis of IGHV-D-J rearrangements from cases in subset 4 with stereotyped IGHV4-34/IGKV2-30 BCRs
| Case no. . | Identity, % . | CM . | UCM . | NMF . | C-AA . | U-AA . |
|---|---|---|---|---|---|---|
| Swe56 | 95.1 | 27 | 11 | 3.05 × 10−3 | 9 | 7 |
| Swe181 | 94.3 | 4 | 1 | 0.94 × 10−3 | 1 | 0 |
| Swe193 | 93.1 | 6 | 4 | 1.65 × 10−3 | 3 | 4 |
| P0103 | 95.9 | 32 | 3 | 2.89 × 10−3 | 11 | 2 |
| P0907 | 93.2 | 6 | 15 | 1.68 × 10−3 | 3 | 10 |
| P1422 | 91.9 | 52 | 12 | 6.27 × 10−3 | 22 | 7 |
| P1939 | 94.5 | 3 | 9 | 0.91 × 10−3 | 1 | 5 |
| P2451 | 91.7 | 39 | 27 | 4.99 × 10−3 | 14 | 15 |
| P2920 | 93.5 | 24 | 19 | 4.38 × 10−3 | 16 | 14 |
| P3020 | 90 | 1 | 4 | 0.83 × 10−3 | 1 | 4 |
| P3551 | 93.3 | 52 | 3 | 7.28 × 10−3 | 25 | 3 |
| P3916 | 91.2 | 3 | 3 | 0.93 × 10−3 | 1 | 1 |
| P6520 | 94.4 | 1 | 8 | 1.08 × 10−3 | 1 | 6 |
| Case no. . | Identity, % . | CM . | UCM . | NMF . | C-AA . | U-AA . |
|---|---|---|---|---|---|---|
| Swe56 | 95.1 | 27 | 11 | 3.05 × 10−3 | 9 | 7 |
| Swe181 | 94.3 | 4 | 1 | 0.94 × 10−3 | 1 | 0 |
| Swe193 | 93.1 | 6 | 4 | 1.65 × 10−3 | 3 | 4 |
| P0103 | 95.9 | 32 | 3 | 2.89 × 10−3 | 11 | 2 |
| P0907 | 93.2 | 6 | 15 | 1.68 × 10−3 | 3 | 10 |
| P1422 | 91.9 | 52 | 12 | 6.27 × 10−3 | 22 | 7 |
| P1939 | 94.5 | 3 | 9 | 0.91 × 10−3 | 1 | 5 |
| P2451 | 91.7 | 39 | 27 | 4.99 × 10−3 | 14 | 15 |
| P2920 | 93.5 | 24 | 19 | 4.38 × 10−3 | 16 | 14 |
| P3020 | 90 | 1 | 4 | 0.83 × 10−3 | 1 | 4 |
| P3551 | 93.3 | 52 | 3 | 7.28 × 10−3 | 25 | 3 |
| P3916 | 91.2 | 3 | 3 | 0.93 × 10−3 | 1 | 1 |
| P6520 | 94.4 | 1 | 8 | 1.08 × 10−3 | 1 | 6 |
All cases shown had confirmed intraclonal diversification (CID)
CM indicates confirmed mutation; UCM, unconfirmed mutation; NMF, normalized mutation frequency; C-AA, confirmed amino acid change; and U-AA, unconfirmed amino acid change.