Main clinical and laboratory features of the analyzed Ph-MPD patients
. | PV . | ET . |
---|---|---|
No. of patients | 13 | 42 |
Sex, male/female | 6/7 | 11/31 |
Mean age, y | 69.3 ± 12.3 | 58.9 ± 17 |
Median follow-up duration, y | 6.71 | 4.8 |
Patients with no thrombosis | 6 | 30 |
Patients with thrombotic complications | 7 | 12 |
Thrombotic events arterial | 4 | 8 |
Thrombotic events venous | 3 | 4 |
Platelet count, ×109/L | 518 ± 220 | 746 ± 167 |
HT ratio | 0.43 ± 0.05 | 0.40 ± 0.04 |
WBC, ×109/L | 11 ± 4.5 | 8.8 ± 2 |
Treatment adopted | ||
Aspirin alone | 1 | 14 |
Phlebotomies alone | 1 | 0 |
HU alone | 3 | 2 |
Warfarin alone | 0 | 4 |
Aspirin and HU | 7 | 14 |
Warfarin and HU | 1 | 1 |
No therapy | 0 | 7 |
. | PV . | ET . |
---|---|---|
No. of patients | 13 | 42 |
Sex, male/female | 6/7 | 11/31 |
Mean age, y | 69.3 ± 12.3 | 58.9 ± 17 |
Median follow-up duration, y | 6.71 | 4.8 |
Patients with no thrombosis | 6 | 30 |
Patients with thrombotic complications | 7 | 12 |
Thrombotic events arterial | 4 | 8 |
Thrombotic events venous | 3 | 4 |
Platelet count, ×109/L | 518 ± 220 | 746 ± 167 |
HT ratio | 0.43 ± 0.05 | 0.40 ± 0.04 |
WBC, ×109/L | 11 ± 4.5 | 8.8 ± 2 |
Treatment adopted | ||
Aspirin alone | 1 | 14 |
Phlebotomies alone | 1 | 0 |
HU alone | 3 | 2 |
Warfarin alone | 0 | 4 |
Aspirin and HU | 7 | 14 |
Warfarin and HU | 1 | 1 |
No therapy | 0 | 7 |
Blood counts refer to the time of the study.
Ph-MPD indicates Philadelphia-negative myeloproliferative disease; PV, polycythemia vera; ET, essential thrombocythemia; HT, hematocrit; and HU, hydroxyurea.