Table 3

Gene Ontology terms and Kyoto Encyclopedia of Genes and Genomes' pathways enriched among the 62 classification marker genes

Annotation type/IDGO term/KEGG pathwayPFold enrichedGene symbols
GO terms     
    GO:0005178 Integrin binding .002 20.04 CTGF, ICAM3, ACTN1 
    GO:0005902 Microvillus .002 52.22 CLIC5, PROM1 
    GO:0003823 Antigen binding .002 21.54 IGJ, LILRA2, IGHD 
    GO:0005834 Heterotrimeric G-protein complex .004 23.93 GNG11, GNAI1 
    GO:0005520 Insulin-like growth factor binding .005 24.98 CTGF, IGF2R 
    GO:0009611 Response to wounding .005 24.98 CTGF, MDK 
    GO:0051015 Actin filament binding .007 16.90 MARCKS, ACTN1 
    GO:0006396 RNA processing .001 12.77 IGF2BP3, RBMS1 
KEGG pathway     
    04810 Regulation of actin cytoskeleton .002 4.78 WASF1, ITGA6, PIK3R3, ACTN1, ARHGEF4 
    04662 B-cell receptor signaling pathway .002 9.47 JUN, PIK3R3, BLNK 
    04510 Focal adhesion .003 5.10 ITGA6, COL6A3, JUN, PIK3R3, ACTN1 
    04512 ECM-receptor interaction .004 6.86 ITGA6, COL6A3, FNDC3A 
    04660 T-cell receptor signaling pathway .004 6.41 JUN, PIK3R3, ZAP70 
    04670 Leukocyte transendothelial migration .006 5.14 PIK3R3, ACTN1, GNAI1 
    04150 mTOR signaling pathway .006 8.46 TSC2, PIK3R3 
    04650 Natural killer cell mediated cytotoxicity .006 4.55 SH2D1A, PIK3R3, ZAP70 
    05211 Renal cell carcinoma .009 5.76 JUN, PIK3R3 
    04640 Hematopoietic cell lineage .01 4.52 ITGA6, CD55 
    04620 Toll-like receptor signaling pathway .01 4.42 JUN, PIK3R3 
    04012 ErbB signaling pathway .01 4.57 JUN, PIK3R3 
Annotation type/IDGO term/KEGG pathwayPFold enrichedGene symbols
GO terms     
    GO:0005178 Integrin binding .002 20.04 CTGF, ICAM3, ACTN1 
    GO:0005902 Microvillus .002 52.22 CLIC5, PROM1 
    GO:0003823 Antigen binding .002 21.54 IGJ, LILRA2, IGHD 
    GO:0005834 Heterotrimeric G-protein complex .004 23.93 GNG11, GNAI1 
    GO:0005520 Insulin-like growth factor binding .005 24.98 CTGF, IGF2R 
    GO:0009611 Response to wounding .005 24.98 CTGF, MDK 
    GO:0051015 Actin filament binding .007 16.90 MARCKS, ACTN1 
    GO:0006396 RNA processing .001 12.77 IGF2BP3, RBMS1 
KEGG pathway     
    04810 Regulation of actin cytoskeleton .002 4.78 WASF1, ITGA6, PIK3R3, ACTN1, ARHGEF4 
    04662 B-cell receptor signaling pathway .002 9.47 JUN, PIK3R3, BLNK 
    04510 Focal adhesion .003 5.10 ITGA6, COL6A3, JUN, PIK3R3, ACTN1 
    04512 ECM-receptor interaction .004 6.86 ITGA6, COL6A3, FNDC3A 
    04660 T-cell receptor signaling pathway .004 6.41 JUN, PIK3R3, ZAP70 
    04670 Leukocyte transendothelial migration .006 5.14 PIK3R3, ACTN1, GNAI1 
    04150 mTOR signaling pathway .006 8.46 TSC2, PIK3R3 
    04650 Natural killer cell mediated cytotoxicity .006 4.55 SH2D1A, PIK3R3, ZAP70 
    05211 Renal cell carcinoma .009 5.76 JUN, PIK3R3 
    04640 Hematopoietic cell lineage .01 4.52 ITGA6, CD55 
    04620 Toll-like receptor signaling pathway .01 4.42 JUN, PIK3R3 
    04012 ErbB signaling pathway .01 4.57 JUN, PIK3R3 

GO indicates Gene Ontology; and KEGG, Kyoto Encyclopedia of Genes and Genomes.

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