Candidate quantitative trait genes prioritized by MeSH analysis
| Gene symbol . | Gene name . | QTL . | MeSH Score . |
|---|---|---|---|
| Trp53 | Transformation related protein 53 | Spl11.2 | 110 |
| Prkdc | Protein kinase, DNA-activated, catalytic polypeptide | Spl16.1 | 39 |
| Xrcc5 | X-ray repair complementing defective repair in Chinese hamster cells 5 | Wbc1.1 | 29 |
| Sfpi1 | SFFV proviral integration 1 | Mleu2.1 | 25 |
| Ercc1 | Excision repair cross-complementing rodent repair deficiency, complementation group 1 | Spl7.1 | 21 |
| Nf1 | Neurofibromatosis 1 | Spl11.2 | 17 |
| Ercc2 | Excision repair cross-complementing rodent repair deficiency, complementation group 2 | Spl7.1 | 14 |
| Piga | Phosphatidylinositol glycan, class A | MleuX.1 | 13 |
| Myc | Myelocytomatosis oncogene | Wbc15.1 | 11 |
| Bcl2 | B-cell leukemia/lymphoma 2 | Mleu1.1 | 9 |
| Trp53bp1 | Transformation-related protein 53 binding protein 1 | Mleu2.1 | 8 |
| Ddb2 | Damage-specific DNA binding protein 2 | Mleu2.1 | 6 |
| Fas | Fas (TNF receptor superfamily member) | Mleu19.1 | 6 |
| Gene symbol . | Gene name . | QTL . | MeSH Score . |
|---|---|---|---|
| Trp53 | Transformation related protein 53 | Spl11.2 | 110 |
| Prkdc | Protein kinase, DNA-activated, catalytic polypeptide | Spl16.1 | 39 |
| Xrcc5 | X-ray repair complementing defective repair in Chinese hamster cells 5 | Wbc1.1 | 29 |
| Sfpi1 | SFFV proviral integration 1 | Mleu2.1 | 25 |
| Ercc1 | Excision repair cross-complementing rodent repair deficiency, complementation group 1 | Spl7.1 | 21 |
| Nf1 | Neurofibromatosis 1 | Spl11.2 | 17 |
| Ercc2 | Excision repair cross-complementing rodent repair deficiency, complementation group 2 | Spl7.1 | 14 |
| Piga | Phosphatidylinositol glycan, class A | MleuX.1 | 13 |
| Myc | Myelocytomatosis oncogene | Wbc15.1 | 11 |
| Bcl2 | B-cell leukemia/lymphoma 2 | Mleu1.1 | 9 |
| Trp53bp1 | Transformation-related protein 53 binding protein 1 | Mleu2.1 | 8 |
| Ddb2 | Damage-specific DNA binding protein 2 | Mleu2.1 | 6 |
| Fas | Fas (TNF receptor superfamily member) | Mleu19.1 | 6 |
All genes within QTLs were queried for Medline citations using the MeSH terms “myelodysplastic syndrome,” “leukemia, myeloid,” “DNA repair,” “metabolic detoxication, drugs,” and “alkylating agents.” Citations for each gene were summed to generate a “MeSH score.” Genes with more than 5 citations are shown here.