Table 1 Summary of hematologic and... | American Society of Hematology

Table 1

Summary of hematologic and survival data from nonleukemic and leukemic mice

	n	Spleen wt, g	WBC count, 10⁹/L	Hb level, g/L	Platelet count, 10⁹/L	Latency, d	Median survival, d	Incidence, %
B6C3F1 −ENU	23
Nonleukemic	20	0.29 ± 0.35	7.73 ± 3.63	125.0 ± 25.8	911.6 ± 215.9
Leukemic	3	1.63 ± 0.48*	213.0 ± 147.4*	89.7 ± 21.6†	458.7 ± 78.5‡	234	NA§	12.5
B6C3F1 +ENU	21
Nonleukemic	6	0.24 ± 0.14	9.07 ± 6.70	120.3 ± 17.8	1032 ± 414.1
Leukemic	12	0.90 ± 0.33‡	56.85 ± 69.59	76.2 ± 29.2†	425.7 ± 245.4‡	199	233	57.1
Lymphoma	3	1.09 ± 0.71	61.11 ± 25.43	86.7 ± 39.9	527 ± 80.0
F₂ −ENU	141
Nonleukemic	29	0.25 ± 0.04	7.95 ± 5.56	119.7 ± 41.0	930 ± 482
Leukemic	112	1.01 ± 0.61*	35.47 ± 71.43	102.7 ± 28.4†	584 ± 298*	108	254	79.4
F₂ +ENU	137
Nonleukemic	4	0.17 ± 0.07	6.50 ± 5.73	139.8 ± 50.2	632.5 ± 209.2
Leukemic	127	1.45 ± 0.63*	115.2 ± 154.9	84.4 ± 29.6*	440.2 ± 214.6	111	171	90.4
Lymphoma	6	1.51 ± 0.76	288.9 ± 392.0	94.8 ± 32.5	506.5 ± 328.8

	n	Spleen wt, g	WBC count, 10⁹/L	Hb level, g/L	Platelet count, 10⁹/L	Latency, d	Median survival, d	Incidence, %
B6C3F1 −ENU	23
Nonleukemic	20	0.29 ± 0.35	7.73 ± 3.63	125.0 ± 25.8	911.6 ± 215.9
Leukemic	3	1.63 ± 0.48*	213.0 ± 147.4*	89.7 ± 21.6†	458.7 ± 78.5‡	234	NA§	12.5
B6C3F1 +ENU	21
Nonleukemic	6	0.24 ± 0.14	9.07 ± 6.70	120.3 ± 17.8	1032 ± 414.1
Leukemic	12	0.90 ± 0.33‡	56.85 ± 69.59	76.2 ± 29.2†	425.7 ± 245.4‡	199	233	57.1
Lymphoma	3	1.09 ± 0.71	61.11 ± 25.43	86.7 ± 39.9	527 ± 80.0
F₂ −ENU	141
Nonleukemic	29	0.25 ± 0.04	7.95 ± 5.56	119.7 ± 41.0	930 ± 482
Leukemic	112	1.01 ± 0.61*	35.47 ± 71.43	102.7 ± 28.4†	584 ± 298*	108	254	79.4
F₂ +ENU	137
Nonleukemic	4	0.17 ± 0.07	6.50 ± 5.73	139.8 ± 50.2	632.5 ± 209.2
Leukemic	127	1.45 ± 0.63*	115.2 ± 154.9	84.4 ± 29.6*	440.2 ± 214.6	111	171	90.4
Lymphoma	6	1.51 ± 0.76	288.9 ± 392.0	94.8 ± 32.5	506.5 ± 328.8

Data are means plus or minus SD (all such values).

WBC indicates white blood cell; Hb, hemoglobin; ENU, ethyl-N-nitrosourea; NA, not applicable.

P < .001 for 2-tailed t tests comparing nonleukemic with leukemic mice.

P < .05 for 2-tailed t tests comparing nonleukemic with leukemic mice.

P < .01 for 2-tailed t tests comparing nonleukemic with leukemic mice.

Median survival not reached.