AML, non-APL patients 70-79 years old (N = 864)
| Region . | Low . | Intermediate . | High . | Comparison: χ2 (P) . | |
|---|---|---|---|---|---|
| Low versus high . | |||||
| All patients | |||||
| Intensive/total (%) | 141/348 (41%) | 153/264 (58%) | 189/252 (75%) | 70 (P ≪ .001) | |
| With intensive therapy | |||||
| PS (0/I/II/III/IV) number | 25/65/25/15/6 | 24/59/41/22/4 | 27/82/52/18/5 | 0.57 (P = .45)* | |
| PS (0/I/II/III/IV) % | 18/48/18/11/4 | 16/39/27/15/3 | 15/45/28/10/3 | ||
| Early death rates | 77/349 (22%) | 50/265 (19%) | 54/253 (21%) | 0.04 (P = .83) | |
| With intensive treatment | 20/141 (16%) | 14/153 (9%) | 31/189 (16%) | 0.30 (P = .58) | |
| With palliation only | 56/207 (27%) | 36/111 (32%) | 22/63 (35%) | 1.46 (P = .23) | |
| CR rates | |||||
| Intensive treatment | 58/141 (41%) | 80/153 (52%) | 93/189 (49%) | 2.12 (P = .15) | |
| Intensive and palliative | 68/349 (19%) | 83/265 (31%) | 93/253 (37%) | 22.3 (P < .001) | |
| Patients alive | |||||
| At 2 y | 24 | 31 | 50 | 22.7 (P < .001) | |
| At 5 y | 1 | 5 | 13 | 15 (P = .001) | |
| Region . | Low . | Intermediate . | High . | Comparison: χ2 (P) . | |
|---|---|---|---|---|---|
| Low versus high . | |||||
| All patients | |||||
| Intensive/total (%) | 141/348 (41%) | 153/264 (58%) | 189/252 (75%) | 70 (P ≪ .001) | |
| With intensive therapy | |||||
| PS (0/I/II/III/IV) number | 25/65/25/15/6 | 24/59/41/22/4 | 27/82/52/18/5 | 0.57 (P = .45)* | |
| PS (0/I/II/III/IV) % | 18/48/18/11/4 | 16/39/27/15/3 | 15/45/28/10/3 | ||
| Early death rates | 77/349 (22%) | 50/265 (19%) | 54/253 (21%) | 0.04 (P = .83) | |
| With intensive treatment | 20/141 (16%) | 14/153 (9%) | 31/189 (16%) | 0.30 (P = .58) | |
| With palliation only | 56/207 (27%) | 36/111 (32%) | 22/63 (35%) | 1.46 (P = .23) | |
| CR rates | |||||
| Intensive treatment | 58/141 (41%) | 80/153 (52%) | 93/189 (49%) | 2.12 (P = .15) | |
| Intensive and palliative | 68/349 (19%) | 83/265 (31%) | 93/253 (37%) | 22.3 (P < .001) | |
| Patients alive | |||||
| At 2 y | 24 | 31 | 50 | 22.7 (P < .001) | |
| At 5 y | 1 | 5 | 13 | 15 (P = .001) | |
Features according to geographical region grouped and ordered according to proportion of patients given intensive therapy.
Value is for PS 0-II versus III-IV.